Search for dissertations about: "replacement"

Showing result 21 - 25 of 987 swedish dissertations containing the word replacement.

  1. 21. Metabolic Effects of Growth Hormone Replacement Therapy in Adults - with Special Reference to Insulin Sensitivity

    Author : Mikael Segerlantz; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; Endokrinologi; sekretion; diabetologi; cortisol replacement; lipid oxidation; glucose metabolism; glucose uptake; insulin resitance; GH; insulin sensitivity; GH deficiency;

    Abstract : A risk for premature atherosclerosis and increased cardiovascular mortality has been reported in adult patients suffering from growth hormone deficiency (GHD) and receiving conventional hormone substitution without growth hormone (GH) replacement. GHD patients are resistant to insulin, which is a potential risk factor for cardiovascular mortality. READ MORE

  2. 22. Removal and Replacement of Ribosomal Proteins : Effects on Bacterial Fitness and Ribosome Function

    Author : Christina Tobin; Dan I. Andersson; Richard Buckingham; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ribosome; protein synthesis; ribosomal proteins; translation initiation; ribosome biogenesis; fitness costs; compensatory evolution; horizontal gene transfer; Microbiology; Mikrobiologi; Biochemistry; Biokemi; Mikrobiologi; Microbiology;

    Abstract : Protein synthesis is a complex process performed by sophisticated cellular particles known as ribosomes. Although RNA constitutes the major structural and functional component, ribosomes from all kingdoms contain an extensive array of proteins with largely undefined functional roles. READ MORE

  3. 23. Cell Replacement Therapy for Parkinson's Disease: Potential for Circuitry Repair

    Author : Tiago Cardoso; Utvecklings- och regenerativ neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rabies-based tracing; Parkinson s disease cell therapy; Cell Replacement Therapy; Human embryonic stem cells; Dopamine neuron; Synaptic integration; circuitry repair;

    Abstract : The derivation of dopamine neurons from human embryonic stem cells (hESCs) now offers a promising alternative to fetal tissue for cell replacement therapy (CRT) in Parkinson´s disease (PD). Using the appropriate chemical cues in vitro, hESCs can be patterned towards bona-fide ventral midbrain (VM) DA neurons that survive, reinnervate, release DA and provide functional recovery when transplanted into rodent and non-human primate models of PD. READ MORE

  4. 24. Cellular replacement therapy for liver disease

    Author : Mohammed Abdel Salam M Saliem; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Liver disease is a major health problem worldwide. The liver performs a wide range of functions, which the human body cannot survive without. The human liver is continuously challenged with infectious organisms, alcohol and chemicals, congenital defects, autoimmunity and malignancy etc. READ MORE

  5. 25. Effect of valve replacement for aortic stenosis on ventricular function

    Author : Ying Zhao; Michael Henein; Per Lindqvist; Eugenio Picano; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aortic stenosis; aortic valve replacement; echocardiography; speckle tracking; exercise echocardiography; ventricular function; septal radial motion; twist; displacement; strain; strain rate;

    Abstract : Background:Aortic stenosis (AS) is the commonest valve disease in the West. Aortic valve replacement (AVR) remains the only available management for AS and results in improved symptoms and recovery of ventricular functions. READ MORE