Search for dissertations about: "replicon organization"

Found 2 swedish dissertations containing the words replicon organization.

  2. 1. Polyamines are involved in the regulation of S phase and DNA synthesis

    Author : Kersti Alm; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Djurfysiologi; Animal physiology; cell cycle regulation; p53; DNA strand breaks; replicon organization; topoisomerase II;

    Abstract : Our research group has previously shown that treatment with the polyamine biosynthesis inhibitors a-difluoromethylornithine (DFMO) or amidinoindan-1-one 2´-amidinohydrazone (CGP 48664) inhibited S phase progression before any other cell cycle phase was affected. This study was undertaken to further investigate the role of polyamines in the regulation of S phase progression and DNA synthesis. READ MORE

  4. 2. Co-operative recombination mechanisms promoting gene clustering and lateral transfer of antibacterial drug resistance

    Author : Masood Kamali-Moghaddam; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Tn5090 Tn402; Mu-like transposons; serine recombinases; res site; integrons; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Pharmaceutical Microbiology; farmaceutisk mikrobiologi;

    Abstract : Transposons of the Mu superfamily are widespread and have been shown to play an important role in the dissemination of antibiotic resistance among microorganisms. One of these elements, Tn5090/Tn402 is the basal vehicle of the type 1 integrons in which mobile resistance gene cassettes are inserted to form clusters and operons. READ MORE