Search for dissertations about: "reproductive organ differentiation"

Showing result 1 - 5 of 6 swedish dissertations containing the words reproductive organ differentiation.

2. 1. Environmental pollutants and the reproductive system in birds : Developmental effects of estrogenic compounds

   Author : Cecilia Berg; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Avian embryo; test system; xeno-estrogen; endocrine disruption; reproductive organ differentiation; oviduct; testis; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Ecotoxicology; ekotoxikologi;

   Abstract : A number of environmental pollutants have been shown to mimick the action of the female sex hormone estrogen and are, therefore, suspected to be responsible for reproductive abnormalities seen in wildlife. Test systems which can be used in hazard and risk assessment of chemicals with estrogenic effects are consequently needed. READ MORE

4. 2. CYSTATIN C AND NEUROENDOCRINE DIFFERENTIATION IN THE MALE REPRODUCTIVE SYSTEM AND IN PROSTATE CANCER

   Author : Thomas Jiborn; Malmö Urologisk cancerforskning; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; androgen deprivation therapy; cysteine protease inhibitor; neuroendocrine differentiation; cysteine protease; male reproductive tract; prostate cancer; nefrologi; Urologi; nephrology;

   Abstract : Cystatins are endogenous protease inhibitors that regulate the proteolytic activities of family C1 (papain-like) cysteine proteases, such as human cathepsins B, H, K, L, and S. Cystatin C shows the fastest inhibition and the highest affinity of all cystatins towards lysosomal cysteine proteases in general and is widespread in human tissues and body fluids. READ MORE

5. 3. Developmental and Reproductive Toxicity of Progestagens in the Xenopus (Silurana) tropicalis Test System

   Author : Moa Säfholm; Cecilia Berg; Ingvar Brandt; Jan Olsson; Louis Guillette; Uppsala universitet; []
   Keywords : Xenopus tropicalis; sex organ differentiation; oogenesis; fertility; ovary; oviduct; progestagens; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

   Abstract : Progestagenic compounds are emerging contaminants found in surface and ground water around the world. Information on the effects and potency of progestagens is needed in order to understand the environmental risks posed by these compounds. READ MORE

6. 4. Roles of ERα and ERβ in Normal and Disrupted Sex Differentiation in Japanese Quail

   Author : Anna Mattsson; Björn Brunström; Krister Halldin; Lena Sahlin; Uppsala universitet; []
   Keywords : Toxicology; sex differentiation; estrogen receptor; sexual behavior; endocrine disruption; Japanese quail; Toxikologi;

   Abstract : Exposure to xenoestrogens during development has been shown to impair sexual differentiation in various species. The major aim of this thesis was to elucidate the respective roles of the two estrogen receptors ERα and ERβ in normal and disrupted differentiation of sex organs and copulatory behavior in the Japanese quail (Coturnix japonica). READ MORE

7. 5. Hematopoietic stem and progenitor cells and potentials for application in fetal cell replacement therapy

   Author : Karina Liuba; Lund Obstetrik och gynekologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; in utero hematopoietic cell transplantation; hematopoietic stem cell; multipotent progenitor; fetal therapy; heterotypic cell fusion;

   Abstract : Fetal cell replacement therapy or in utero hematopoietic cell transplantation (IUHCT) is proposed as a non-myeloablative alternative to bone marrow transplantation (BMT) for a number of inborn immunologic, hematologic and metabolic disorders. IUHCT represents the method through which variable amounts of natural or genetically modified hematopoietic cells can be transferred to the fetal recipient in hope of correcting the disorder and preventing postnatal permanent organ damage. READ MORE