Search for dissertations about: "rescue neural"

Showing result 1 - 5 of 10 swedish dissertations containing the words rescue neural.

  2. 1. Neural stem cell engraftment : functional interactions, brain repair and gap junctions

    Author : Johan Jäderstad; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Neural stem cell (NSC) engraftment therapies show increasing promise as potential cures for several of the diseases of the central nervous system. Traditionally, functional improvements after NSC engraftment have been attributed to replacement of lost neurons and astrocytes, remyelination and support of adjacent cells at risk. READ MORE

  4. 2. Investigating the role of neural stem/progenitor regulators in the context of brain tumor development

    Author : Isabelle Leefa Chong San; Stamcellscentrum (SCC); []
    Keywords : neural stem progenitor cells; regulators; brain tumor; cell of origin; cancer mechanisms;

    Abstract : Adult neural stem/progenitor cells (NSPs) are multipotent and self-renew over an extensive period of time. Transformation events in such cells, such as genetic or epigenetic alterations can result in brain tumors. READ MORE

  5. 3. Cell interactions in the CNS and their consequences for neuronal apoptosis

    Author : Mikaela Berglund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Aggregate cultures; apoptosis; automated image analysis; cytochrome c; interactions; JNK; microglia; neuron; neural precursor cells; rotenone; UV.;

    Abstract : The central nervous system consists of an intricate network of neurons and glial cells that depend on reciprocal communication to develop and maintain the vital functions of the brain. if the balance is disturbed by injury or disease, two cell types in particular, microglia and astrocytes, respond by producing factors that help combat the infection or delimit the affected area. READ MORE

  6. 4. Brain development in a dish

    Author : Robin Johan Pronk; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis shows the path I took in the quest for modeling the brain, as the title says, in a dish. The introduction of induced pluripotent stem cells (iPSCs) as means to research biological processes has opened up whole new fields of study and unprecedented possibilities of generating human cells in vitro. READ MORE

  7. 5. Stem cell interactions with the injured brain

    Author : Linda Maria Jäderstad; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Neurodegenerative diseases such as Parkinson's disease, Huntington's disease and amyotrophic lateral sclerosis and acute neurological disorders such as brain ischemia and traumatic injury yearly affect millions of people. Neural stem cell (NSC) grafting is an emerging strategy to treat and potentially cure these conditions for which today no effective remedies exist. READ MORE