Search for dissertations about: "resistin"

Showing result 1 - 5 of 13 swedish dissertations containing the word resistin.

  1. 1. Resistin is a modulator of inflammation and autoimmunity

    Author : Elisabeth Almer Boström; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Resistin; inflammation; autoimmunity; rheumatoid arthritis; Sjögren s syndrome;

    Abstract : Resistin is a protein with proinflammatory properties in man and a regulator of glucose metabolism in mice. Human resistin activates the nuclear factor kappa-B dependent cytokine cascade; however, its full role in inflammation in terms of regulation, expression, and cellular source is not entirely understood. READ MORE

  2. 2. Intestinal transplantation. Experimental and clinical studies

    Author : Mihai Oltean; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Intestinal preservation; Ischemia-reperfusion injury; Tight junction; FK506; Resistin;

    Abstract : Intestinal preservation-reperfusion injury may result in various degrees of mucosal injury. Interestingly, the preservation injury is similar when using the current preservation solutions, which are given as a intravascular flush. An extensive mucosal injury may ultimately preclude the use of organs that require longer preservation time. READ MORE

  3. 3. Osteoporosis in SLE

    Author : Katarina Almehed; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : osteoporosis; systemic lupus erythematosus; bone mineral density; health-related quality of life; SF-36; resistin; cross sectional study; vertebral fracture;

    Abstract : As the treatment of Systemic Lupus Erythematosus (SLE) has become more effective the focus has partly shifted from main concern of short term morbidity and survival to long term complications such as osteoporosis. The aims of this thesis were to a) determine prevalence and risk factors of osteoporosis and of b) vertebral fractures c) evaluate if adequate osteoporotic treatment was provided d) determine if resistin, an adipokine with proposed pro-inflammatory properties, was associated with markers of inflammation or bone mineral density (BMD) and to e) investigate patients self reported health related quality of life (HRQOL) and its relationship to disease variables and employment status in female SLE patients. READ MORE

  4. 4. Prolactin receptor expression and prolactin-mediated effects in adipose tissue

    Author : Charlotte Ling; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : adipose tissue; prolactin receptor; SOCS; leptin; resistin; lipoprotein lipase;

    Abstract : The aim of this study was to investigate the presence of functional prolactin receptors (PRLRs) in white adipose tissue of mice and humans, and the possible functions mediated via PRLRs. In mouse white adipose tissue, three PRLR mRNA isoforms, L-, S2-, and S3-PRLR, and L-PRLR protein expression were detected. READ MORE

  5. 5. On the role of HMGB1 and resistin in severe sepsis and septic shock

    Author : Jonas Sundén-Cullberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Severe sepsis and septic shock are serious manifestations of infectious diseases. Mortality ranges from over 30 % in severe sepsis up to 60% in septic shock. Early antibiotic treatment and intensive care are mainstays of therapy, but outside of this, new treatments have only marginally improved survival. READ MORE