Search for dissertations about: "retinal vascularization"

Found 4 swedish dissertations containing the words retinal vascularization.

  2. 1. Born too small or too early : effects on blood pressure, renal function and retinal vascularization in adulthood : experimental and clinical studies

    Author : Anna Kistner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Prenatal dexamethasone; SGA; preterm birth; glomerular filtration rate; ambulatory blood pressure; retinal vascularization; IGF-I; IGFBP-1; metabolic serum markers;

    Abstract : Background: Several epidemiological studies the past fifteen years have suggested a connection between fetal growth retardation and later effects on adult health, such as an increased arterial blood pressure and type 2 diabetes mellitus. We studied the effects of fetal growth retardation in an experimental model were pregnant rats where given the synthetic glucocorticoid dexamethasone (DEX). READ MORE

  4. 2. Sex steroids, IGF-I, and vascular morphology from birth to adulthood in individuals born small for gestational age

    Author : Kerstin Allvin; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small for gestational age; preterm; sex steroid; estradiol; testosterone; dihydrotestosterone; glucocorticoid; retina; IGF-I;

    Abstract : Abstract Aim: To study whether there is an association between size at birth, sex steroids, IGF-I, and retinal vascular morphology. Patients and methods: Two different cohorts were studied. In paper I, 25 young adult men born small for gestational age (SGA) were compared to 44 young adult men born appropriate for gestational age (AGA). READ MORE

  5. 3. A frizzled quest to dissect the molecular pharmacology of WNT signaling : from biology to signaling mechanism(s)

    Author : Elisa Arthofer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The wingless/int1 (WNT)/Frizzled (FZD) family of signal transduction pathways is highly conserved across species and controls essential physiological functions important for embryonic development, stem cell renewal, proliferation, differentiation, and cell polarity. Dysregulation of these signaling pathways leads to developmental abnormalities or other conditions such as inflammation, cancer, or neurological disorders. READ MORE

  6. 4. Tumor angiogenesis. Regulation of mural cell recruitment and endothelial sprouting

    Author : Alexandra Abramsson; Göteborgs universitet; []
    Keywords : Angiogenesis; tumor; retina; PDGF; VEGF; platelet-derived growth factor; guidance; vascular endothelial growth factor.;

    Abstract : The formation of new blood vessels is an inherent part of many physiological and pathological processes. Currently, there is a strong hope pathological situations like stroke, diabetic retinopathy and cancer may be affected by pharmacological regulators of blood vessel formation. READ MORE