Search for dissertations about: "retinoic acid."

Showing result 1 - 5 of 121 swedish dissertations containing the words retinoic acid..

  1. 1. Effects of retinoic acid in the mouse olfactory sensory systems

    Author : Maria Hörnberg; Staffan Bohm; Finn Hallböök; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; olfactory; retinoic acid; neuron survival; Molecular biology; Molekylärbiologi;

    Abstract : A common characteristic in neurodegenerative diseases of the brain is death of specific neuronal populations. The lack of neuron proliferation and axon extension in most parts of the central nervous system leads to chronic loss of neurons in the case of injury or disease. READ MORE

  2. 2. Thymic Stroma and T Cell Development. Impacts of Retinoic Acid Signaling

    Author : Kerstin Wendland; Slemhinnans immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thymus; Thymic epithelial cells; Retinoic acid; T cell development; Stromal Cells;

    Abstract : The development of functionally competent, self-tolerant T cells in the thymus is an essential prerequisite for the formation of adaptive immune responses against foreign pathogens. Thymic epithelial cells (TECs) form specialized stromal microenvironments in the cortex (cTEC) and medulla (mTEC) of the thymus that support all stages of T cell development, from the entry of thymocyte progenitors to the exit of mature naive T cells. READ MORE

  3. 3. CYP26B1 as regulator of retinoic acid in vascular cells and atherosclerotic lesions

    Author : Ali Ateia Elmabsout; Allan Sirsjö; Karin Fransén; Helen Håkansson; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP26B1; alternative splice; vascular cells; atherosclerosis; alltrans-retinoic acid; gene polymorphism; inflammation; statins; Medicin; Medicine;

    Abstract : Cardiovascular disease (CVD), currently the most common cause of morbidity and mortality worldwide, is caused mainly by atherosclerosis. Atherosclerosis is a chronic multifocal, immunoinflammatory, fibroproliferative disease of medium and large arteries. READ MORE

  4. 4. Retinoic Acid Metabolism Blocking Agents and the Skin : In vivo and in vitro Studies of the Effects on Normal and Diseased Human Epidermis

    Author : Elizabeth Pavez Loriè; Anders Vahlquist; Hans Törmä; Marie Virtanen; Helen Håkansson; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP; CYP26; retinoids; vitamin A; RAMBA; metabolism; keratinocyte; epidermis; retinoid regulated genes; Dermatology and venerology; Dermatologi och venerologi;

    Abstract : Retinoic Acid Metabolism Blocking Agents (RAMBAs) increase the endogenous levels of all-trans retinoic acid (RA) by inhibiting CYP26 enzymes. Thus they are believed to mimic the effects of retinoid treatment. Their mechanism of action and effects on vitamin A metabolism in keratinocytes are however uncertain. READ MORE

  5. 5. Effects of ellagic acid in human neuroblastoma cells

    Author : Christina Fjæraa Alfredsson; Eewa Nånberg; Karin Persson; Karlstads universitet; []
    Keywords : polyphenols; ellagic acid; neuroblastoma; SH-SY5Y cells; differentiation; proliferation; apoptosis; cell adhesion; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : A diet rich in polyphenols has been proposed to have beneficial health effects and to reduce risk of disease. Ellagic acid, a polyphenol common in red berries and pomegranates, has potential anti-tumorigenic effects that make it interesting to further study in different cancer cell systems. READ MORE