Search for dissertations about: "retinoic acid."
Showing result 11 - 15 of 129 swedish dissertations containing the words retinoic acid..
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11. Regulation of tissue factor expression in myeloid and monocytic leukaemia cells
Abstract : Tissue factor (TF) is a transmembrane glycoprotein that initiates the blood coagulation cascade and is also involved in cell migration, tumour metastasis and angiogenesis. Pathologic expression of tissue factor by monocytes contributes to several thrombotic complications like acute coronary artery disease and disseminated intravascular coagulation. READ MORE
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12. Regulation of morphogen signalling during neural patterning in the Xenopus embryo
Abstract : Morphogens such as Hedghog, Wnt, FGF, and retinoic acid are important signals whose concentrations need to be tightly regulated in the vertebrate embryo to ensure body axis development and formation of the central nervous system. We first show that the intracellular cytoplasmic protein XSufu acts as a dual regulator of Hedgehog (Hh) and Wnt signals during neural induction and patterning in the Xenopus embryo. READ MORE
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13. Selenoproteins in the Bovine Mammary Gland. Regulation of mRNA and Protein Expression
Abstract : Selenium is a micronutrient that is essential for many important life processes due to the action of the specific selenoproteins containing one or more of the 21st amino acid, selenocysteine. Twenty-five selenoprotein genes have been found in the human genome but the function of many of them is not yet known. READ MORE
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14. Studies on Human Endogenous Retroviruses (HERVs) with Special Focus on ERV3
Abstract : Human endogenous retroviruses (HERVs) represent approximately 7% of the human genome. This investigation was focused on one particular HERV, ERV3, with the main purpose of characterising its gene expression patterns and genomic distribution of ERV3-like sequences. READ MORE
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15. Proteolytic processing of the Alzheimer APP protein family during neuronal differentiation
Abstract : Increased amyloid-β (Aβ) load in the brain, neurite degeneration, neuronal loss, and decreased levels of several neurotrophins are among the characteristics of Alzheimer’s disease (AD). Generation of Aβ occurs when the amyloid precursor protein (APP) is proteolytically processed by β- and γ-secretases in the amyloidogenic pathway. READ MORE