Search for dissertations about: "retinol-binding protein 4"

Showing result 1 - 5 of 11 swedish dissertations containing the words retinol-binding protein 4.

  2. 1. Effects of prolactin on metabolism - changes induced by hyperprolactinemia

    Author : Louise Nilsson; Göteborgs universitet; []
    Keywords : prolactin; prolactin receptor; hyperprolactinemia; adipose tissue; lipoprotein lipase; malonyl-CoA; glucose transporter 4; retinol-binding protein 4; adiponectin; lipid oxidation;

    Abstract : High prolactin levels during breast-feeding, is recognized to influence metabolism in order to supply glucose and fat for milk production. Pathologic overproduction of prolactin, hyperprolactinemia, is a condition primarily associated with reproductive disorders; however, the metabolic impact of elevated prolactin indicates that these parameters might be considered in clinical management of the condition. READ MORE

  4. 2. Urinary Clara cell protein and alpha 1-microglobulin – biomarkers of changes in kidney and airway function

    Author : Lena Andersson; Göteborgs universitet; []
    Keywords : biomarker; Clara cell 16 kDa protein CC16 ; alpha 1-microglobulin A1M ; ambient air pollution; renal function; pyelonephritis; children;

    Abstract : Validated biomarkers are useful tools for screening large populations. The benefit of screening may be improved risk assessment or early indications of adverse effects before detection or onset of symptoms. READ MORE

  5. 3. Studies on the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on vitamin A homeostasis

    Author : Charlotte Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : TCDD; dioxin; vitamin A; retinoic acid; lecithin:retinol acyltransferase; retinyl ester hydrolysis; retinol-binding protein; kidney; lymph; stellate cell; kinetics; model-based compartmental analysis;

    Abstract : Vitamin A (retinoids) is needed for normal vision, growth, reproduction, cell differentiation, embryonic development, and immune function. Retinoids exert their functions in the same way as classical hormones, as transcription factors acting via nuclear receptors. READ MORE

  6. 4. Disruption of vitamin A metabolism by dioxin

    Author : Pi Högberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : TCDD; dioxin; vitamin A; retinoic acid; cellular retinol-binding protein; bone;

    Abstract : Vitamin A (retinoids) is a nutrient that plays a central role in development and remains essential for cell growth and differentiation throughout life. Dioxins are polychlorinated organic pollutants known to negatively affect the storage and body clearance of retinoids. READ MORE

  7. 5. Molecular Aspects of Transthyretin Amyloid Disease

    Author : Karin Sörgjerd; Per Hammarström; Joel Buxbaum; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloid; apoptosis; BiP; chaperone; misfolding; oligomer; transthyretin; Biochemistry; Biokemi;

    Abstract : This thesis was made to get a deeper understanding of how chaperones interact with unstable, aggregation prone, misfolded proteins involved in human disease. Over the last two decades, there has been much focus on misfolding diseases within the fields of biochemistry and molecular biotechnology research. READ MORE