Search for dissertations about: "retransfusion"

Showing result 1 - 5 of 9 swedish dissertations containing the word retransfusion.

  1. 1. Aspects of retransfusion of shed blood in cardiac surgery

    Author : Björn Brondén; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CABG; cardiotomy suction; lipid microemboli; porcine study; clinical study; cystatin C; creatinine; iohexol clearance; outcome; retransfusion; transfusion; blood.;

    Abstract : The use of cardiotomy suction during open heart surgery with cardiopulmonary bypass (CPB) has a long tradition and often regarded as mandatory. Recently, studies have described potentially negative effects of cardiotomy suction with activation of the complement system, enhanced inflammatory response, hemolysis and coagulopathy. READ MORE

  2. 2. Heparin coating and cardiotomy suction in cardiopulmonary bypass

    Author : Staffan Svenmarker; Torkel Åberg; Gunnar Engström; Thomas Karlsson; Jarle Vaage; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; cardiopulmonary bypass; oxygenators; heparin; S100 proteins; blood loss; haemostasis; memory; outcome and process assessment; Kirurgi; Surgery; Kirurgi; kirurgi; Surgery;

    Abstract : The present thesis addresses various means of reducing inflammatory responses associated with cardiopulmonary bypass (CPB) and retransfusion of pericardial suction blood (PSB) during cardiac surgery. Four (I-IV) prospective randomised controlled clinical trials comprising 475 patients were performed in the following areas: effects of heparin coating on measures of clinical outcome and memory function (I, II), inflammatory reactions in PSB and its systemic effects after retransfusion using cardiotomy suction or cell salvage (III) and effects of retransfusion of PSB on memory function and release patterns of protein S100B (IV). READ MORE

  3. 3. S100B and Cardiac Surgery

    Author : Henrik Bjursten; Thoraxkirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; S100-B; S100B; S100beta; brain damage; cardiac surgery; CABG; renal function; autotransfusion; Cardiovascular system; serum marker; Kardiovaskulära systemet;

    Abstract : The brain-derived protein S100B is a 21 Kda dimerand have been used as a serum marker for brain damage of different etiology. The feasability of protein S100B as serum marker for brain damage after cardiac surgery was studied in this thesis. One unexpected finding was made, which changed the basis for interpration of S100B levels. READ MORE

  4. 4. Systemic inflammatory activation during cardiac Surgery. Influence of cardiopulmonary bypass management and patient factors

    Author : Martin Westerberg; Göteborgs universitet; []
    Keywords : cardiopulmonary bypass; inflammatory response; coagulation; CABG; cardiotomy suction; cytokines;

    Abstract : Cardiac surgery with cardiopulmonary bypass is accompanied by a prominent systemic inflammatory and hemostatic activation, which may contribute to postoperative complications. Aims: To investigate if selection of cardiopulmonary bypass (CPB) system and management of cardiotomy suction (CTS) and mediastinal shed blood (MSB) affect systemic inflammatory response. READ MORE

  5. 5. Hemostatic function and inflammatory activation after weaning from cardio pulmonary bypass

    Author : Anki Olsson; Sören Berg; Joakim Alfredsson; Rolf Svedjeholm; Erik Håkansson; Tomas Gudbjartsson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cardiopulmonary bypass (CPB) contributes to perioperative platelet dysfunction, increased fibrinolysis and impaired coagulation, which can have an impact on postoperative bleeding. During CPB the blood is exposed to foreign surfaces leading to activation of the coagulation system and a systemic inflammatory response with complement and leukocyte activation. READ MORE