Search for dissertations about: "retrograde signaling"

Showing result 1 - 5 of 14 swedish dissertations containing the words retrograde signaling.

  2. 1. Signaling and Adhesive Mechanisms in Acute Pancreatitis

    Author : Darbaz Awla; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; trypsinogen activation; Acute pancreatitis; leukocyte recruitment and adhesion;

    Abstract : Acute pancreatitis (AP) is an inflammatory disease with variable severity ranging from mild interstitial edematous to severe necrotizing disease. The overall mortality rate of AP is 8-9%. Specific treatment of AP is lacking which is partly related to an incomplete understanding of the basic pathophysiology behind the disease. READ MORE

  4. 2. The secret life of nuclear IGF-1R : functions beyond traditional signaling pathways

    Author : Dudi Warsito; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The implications of IGF-1R in normal development and disease are well established. IGF-1R plays pivotal roles in cell proliferation and cell survival and aberrant activation result in tumorigenesis and cancer progression. READ MORE

  5. 3. Neocortical layer 2/3 microcircuits

    Author : Carl Holmgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Neocortical microcircuit; layer 2 3; pyramidal cell; FSN interneuron; retrograde signaling; VGLUT3; spike-timing dependent plasticity; LTP; LTD.;

    Abstract : Pairs of interconnected neurons form elementary information processing units within neocortical microcircuits. Pyramidal cells within these microcircuits receive synaptic input, both from their connected partners, and from more distant cortical and sub-cortical regions. Consequently, they require a means to identify relevant synaptic signals. READ MORE

  6. 4. Get in tune : chloroplast and nucleus harmony

    Author : Dmitry Kremnev; Åsa Strand; Francis-Andre Wollman; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Arabidopsis thaliana; chloroplast; development; gene expression;

    Abstract : Photosynthetic eukaryots emerged as a result of several billion years of evolution between proeukaryotic cell and ancestral cyanobacteria that formed modern chloroplasts. The symbiotic relationship led to significant rearrangements in the genomes of the plastid and the nucleus: as many as 90 % of all the plastid genes were transferred to the nucleus. READ MORE

  7. 5. Neuromodulation via endocannabinoids and nitric oxide in the lamprey spinal cord

    Author : Alexandros Kyriakatos; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The overall objective of this thesis is to increase our understanding of neural networks generating locomotion. These networks called Central Pattern Generators (CPG), are localized in the spinal cord and can generate the basic locomotor pattern in the absence of sensory or supraspinal inputs. READ MORE