Search for dissertations about: "reumatologi"

Showing result 21 - 25 of 226 swedish dissertations containing the word reumatologi.

2. 21. Genetic Contributions to Manifestations and Prognosis of Systemic Lupus Erythematosus

   Author : Sarah Reid; Dag Leonard; Timothy Niewold; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic lupus erythematosus; genetics; cardiovascular disease; polygenic risk score; smoking; Medicinsk vetenskap; Medical Science;

   Abstract : Systemic lupus erythematosus (SLE) is a severe autoimmune disease with a multifactorial aetiology and an extremely heterogenous clinical picture. This thesis explores the impact of SLE genetic variants, through their cumulative effect or gene-environment interactions, on SLE manifestations and complications. READ MORE

4. 22. Atherosclerotic cardiovascular disease in rheumatoid arthritis : aspects of pathogenesis and risk

   Author : Bengt Wahlin; Solveig Wållberg-Jonsson; Anna Södergren; Anders Bengtsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; inflammation; atherosclerosis; cardiovascular disease; risk estimation; cytomegalovirus; T-cells; bone turnover; osteoprotegerin; osteocalcin; Medicine; medicin;

   Abstract : Patients with rheumatoid arthritis (RA) have an increased prevalence and severity of atherosclerosis, and a corresponding increased risk of cardiovascular disease. The mechanisms causing this are not well elucidated, but both traditional cardiovascular risk factors and RA-associated factors have been associated with atherosclerosis and increased risk of cardiovascular events in patients with RA. READ MORE

5. 23. Aerobic capacity in rheumatoid arthritis : aspects of associations with cardiovascular risk factors and disease activity

   Author : Lars Ångström; Anna Södergren; Solveig Wållberg Jonsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Rheumatoid arthritis (RA) is a systemic and inflammatory disease that has been associated with an increased morbidity and mortality in cardiovascular disease (CVD). Low aerobic capacity is one of the strongest independent risk factors for CVD and all-cause mortality in the general population. READ MORE

6. 24. On the etiology and pathogenesis of systemic lupus erythematosus with special reference to environmental factors

   Author : Anders Bengtsson; Reumatologi och molekylär skelettbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Skeleton; Risk factors; Human parvovirus B19; Immune complex; Disease activity; Interferon-alpha; SLE; Retrovirus;

   Abstract : Systemic lupus erythematosus (SLE) is a complex autoimmune disease in which environmental factors interact with genetic factors in the development of the disease process and evolution of clinical manifestations. In this thesis both exogenous factors and host factors were investigated, as well as important immunopathological aspects including involvement of immune complex (IC), the complement system and interferon-alpha (IFN-α). READ MORE

7. 25. Chronic musculoskeletal pain: a multifactorial process

   Author : Stefan Bergman; Reumatologi och molekylär skelettbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; widespread; SF-36; risk factors; rheumatoid arthritis; pain; musculoskeletal; epidemiology; fibromyalgia; Skeleton; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi;

   Abstract : The aim was to study prevalence, assessment methods, and risk factors of chronic musculoskeletal pain, as well as effects on health status in a general population setting. A postal survey to a representative sample of 3928 subjects aged 20–74 years in 2 municipalities on the west coast of Sweden was followed by clinical examinations of selected subjects, and a three-year follow up survey to 2425 subjects who answered completely to the first. READ MORE