Search for dissertations about: "rheumatoid arthritis combined therapy"

Showing result 1 - 5 of 9 swedish dissertations containing the words rheumatoid arthritis combined therapy.

  2. 1. B cell subpopulations in the pathogenesis of rheumatoid arthritis

    Author : Katrin Thorarinsdottir; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; B cells; Rheumatoid arthritis; Joint destruction; DAS28; CD21- low B cells;

    Abstract : B cell depleting therapy has proven to be an effective treatment in rheumatoid arthritis (RA), a disease characterized by the presence of autoantibodies against citrullinated proteins (ACPA) and the Fc portion of IgG (rheumatoid factor, RF). This demonstrates the vital role B cells play in the disease. READ MORE

  4. 2. Oxidative stress and muscle weakness associated with rheumatoid arthritis

    Author : Maarten Michiel Steinz; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Muscle weakness is a common comorbidity of several severe diseases which results in a reduced independence and quality of life and for the afflicted patients. For instance, patients with rheumatoid arthritis (RA), a disease characterized by a chronic inflammation of the joints, commonly report of muscle weakness as a complication. READ MORE

  5. 3. The association between hormonal/reproductive factors and the risk of developing rheumatoid arthritis

    Author : Cecilia Orellana Pozo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rheumatoid arthritis (RA) is a chronic inflammatory disease which leads to joint damage and bone destruction, with a complex interplay of genetic and environmental factors involved in its etiology. RA is more common among women than men at all ages, but the gender difference seems to be highest before menopause. READ MORE

  6. 4. The impact of autoimmune thyroid disease (AITD) on rheumatoid arthritis (RA) and the impact of RA on AITD

    Author : Kristin Waldenlind; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Study I. Background: The Swedish National Patient Register (NPR) is a unique source for the identification of large cohorts of rheumatoid arthritis (RA) patients. The general validity of this register has been reported to be high. READ MORE

  7. 5. Genetic variations in the NALP3 inflammasome: a susceptibility factor for inflammatory diseases

    Author : Deepti Verma; Peter Söderkvist; Ulf Andersson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammasome; Interleukin-1 beta; NALP3; autoinflammation; Medical genetics; Medicinsk genetik;

    Abstract : Innate immunity has received impressive attention in the past decade owing to the discovery of the Toll like receptors (TLRs) and the NOD-like receptors (NLRs). While the TLRs specialize in fighting microbes at the cell surface, the NLRs complement by detecting and responding to intracellular microbes. READ MORE