Search for dissertations about: "rheumatoid-arthritis"

Showing result 16 - 20 of 478 swedish dissertations containing the word rheumatoid-arthritis.

  1. 16. Autoantibodies and genetic variation in rheumatoid arthritis : aspects on susceptibility and disease course

    Author : Alf Kastbom; Thomas Skogh; Peter Söderkvist; Alex Karlsson-Parra; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; autoantibodies; single-nucleotide polymorphisms; disease course; Rheumatology; Reumatologi;

    Abstract : Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and subsequent destruction of synovial joints. Although its causes remain largely unknown, a substantial genetic contribution is known to exist. READ MORE

  2. 17. Aspects of physical activity in Rheumatoid Arthritis : associations with inflammation and cardiovascular risk factors

    Author : Kristina Hörnberg; Solveig Wållberg Jonsson; Björn Sundström; Christina Helging Opava; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; physiotherapy; rheumatoid arthritis; cardiovascular disease; aerobic capacity; physical activity; exercise; primary prevention;

    Abstract : Background: Rheumatoid Arthritis (RA) is associated with an increased risk for cardiovascular disease (CVD), partially attributable to systemic inflammation and traditional risk factors for CVD. Since physical activity (PA) is strongly related to CVD in the general population, the aim of this thesis was to describe aspects of PA in patients with RA, and further to analyse associations with disease activity, traditional risk factors for CVD and subclinical atherosclerosis. READ MORE

  3. 18. Aspects of Disability in Rheumatoid Arthritis : a five-year follow-up in the Swedish TIRA project

    Author : Mathilda Björk; Björn Gerdle; Ingrid Thyberg; Thomas Skogh; Klas Rikner; Karin Harms-Ringdahl; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis RA ; disability; hand function; pain intensity; ADL; sick leave; prediction; Rheumatology; Reumatologi;

    Abstract : Rheumatoid arthritis (RA) is a progressive disease, often leading to disability. Because the disease course develops rapidly during the first years after diagnosis, more knowledge is needed about the early disease course to minimize later disability. READ MORE

  4. 19. Genetic Studies of Rheumatoid Arthritis using Animal Models

    Author : Niklas Nordquist; William Dietrich; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Complex disease; autoimmune; rheumatoid arthritis; genetic; mapping; QTL; locus; linkage; animal model; rat; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Abstract : Predisposition to autoimmune diseases such as, rheumatoid arthritis, diabetes, and multiple sclerosis, is caused by the effect of multiple genes and a strong influence from the environment. In this study, I have investigated genetic factors that confer susceptibility to rheumatoid arthritis in a rat model. READ MORE

  5. 20. Rheumatoid Arthritis: Body Composition, Bone Loss, and Mortality

    Author : Christina Book; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fat mass; bone mass; lean mass; body composition; mortality; rheumatoid arthritis; predictors;

    Abstract : Early rheumatoid arthritis (RA) patients (disease duration ≤1 year, n=165) were recruited 1995-2001 and followed systematically clinically and with dual energy X-ray absorptiometry (DXA) over 2 years and compared to age- and gender-matched controls. Baseline arm and leg lean mass were decreased in RA patients in both genders and body mass index and truncal fat distribution were increased in female RA patients. READ MORE