Search for dissertations about: "rheumatoid"

Showing result 1 - 5 of 416 swedish dissertations containing the word rheumatoid.

  1. 1. Extra-articular Rheumatoid Arthritis Risk Factors and Consequences

    University dissertation from Lund University, Faculty of Medicine

    Author : Britt-Marie Nyhall-Wahlin; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiographic progression; disease activity burden; smoking; rheumatoid nodules; Rheumatoid arthritis; extra-articular manifestations; TNF-inhibitor treatment;

    Abstract : Rheumatoid arthritis (RA) is a systemic disease not only restricted to the joints, but can also be associated with the development of extra-articular manifestations. Extra-articular RA (ExRA) is of clinical importance because of the associated morbidity and increased risk of premature mortality compared with RA patients in general. READ MORE

  2. 2. Genetic markers in rheumatoid arthritis

    University dissertation from Umeå : Umeå universitet

    Author : Solbritt Rantapää Dahlqvist; Umeå universitet.; [1985]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; family history; genetic marker; HLA B27; HLA DR4; properdin factor B; C3 complement; -antitrypsin; haptoglobin; transferrin;

    Abstract : Genetic as well as environmental factors are believed to be of importance in the etiology of rheumatoid arthritis (RA). There are a number of previous studies of genetic markers in RA, but so far no genetic linkage and only a few associations have been found. Of the associations only one (with the HLA antigen DR4) appears to be well documented. READ MORE

  3. 3. Pharmacometric Modeling in Rheumatoid Arthritis

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Brigitte Lacroix; Uppsala universitet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; PKPD; immunogenicity; ACR; IPPSE; certolizumab pegol;

    Abstract : Biologic therapies have revolutionized the treatment of rheumatoid arthritis, a common chronic inflammatory disease, mainly characterized by the chronic inflammation of the joints. The activity and progression of the disease are highly variable, both between subjects and between the successive assessments for the same subject. READ MORE

  4. 4. Disease activity in rheumatoid arthritis Studies in interleukin-6, tumour necrosis factor alpha, monocyte activity, acute phase markers, glucocorticoids, and disability

    University dissertation from Uppsala : Institutionen för medicinska vetenskaper

    Author : Nils Gunnar Arvidson; Uppsala universitet.; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemistry; acute phase markers; circadian rhythm; disability; disease activity; glucocorticoids; monocyte activation; rheumatoid arthritis; Kemi; NATURAL SCIENCES Chemistry; NATURVETENSKAP Kemi; Medicine; medicin;

    Abstract : In the present studies, aspects of some disease activity measures in rheumatoid arthritis (RA) have been investigated, including the effect of glucocorticoids on this activity. In RA, serum interleukin(IL)-6 levels were elevated and were shown to have a circadian rhythm, with peak levels in the morning, declining towards low or normal levels in the afternoon and evening. READ MORE

  5. 5. Predictors of disease onset and progression in early rheumatoid arthritis A clinical, laboratory and radiological study

    University dissertation from Umeå : Folkhälsa och klinisk medicin

    Author : Ewa Berglin; Umeå universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; early; rheumatoid; arthritis; anti-CCP; antibodies; factors; radiological; outcome; disease; onset; Medicin; MEDICINE Dermatology and venerology; clinical genetics; internal medicine; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Medicine; medicin;

    Abstract : To diagnose rheumatoid arthritis (RA) during the early stages of the disease is often difficult. The disease course shows great inter-individual variation from mild, self-limiting to very severe destruc-tive disease with extra-articular manifestations. READ MORE