Search for dissertations about: "rheumatology"

Showing result 1 - 5 of 240 swedish dissertations containing the word rheumatology.

  1. 1. Immunological mechanisms in systemic autoimmunity autoantibodies and chemokines in systemic lupus erythematosus and during treatment with TNF inhibitors in rheumatoid arthritis

    University dissertation from Umeå : Umeå Universitet

    Author : Catharina Eriksson; Karl-Gösta Sundqvist; Solbritt Rantapää-Dahlqvist; Mari Norgren; Thomas Skogh; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmunity; chemokines; T-cells; autoantibodies; CD91; MEDICINE Microbiology; immunology; infectious diseases Immunology Clinical immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi Klinisk immunologi; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Rheumatology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Reumatologi; Clinical Immunology; klinisk immunologi; reumatologi; rheumatology;

    Abstract : Background. Rheumatoid Arthritis (RA) is an autoimmune inflammatory disease that, without powerful treatment, may lead to irreversible joint damage. During the past decade, anti-cytokine therapy has become available, e.g. READ MORE

  2. 2. On the immunopathogenesis of systemic lupus erythematosus - Immune complexes, type I interferon system, complement system and platelets

    University dissertation from Section of Rheumatology, Dept of Clinical Sciences, Lund

    Author : Christian Lood; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; systemic lupus erythematosus; autoimmunity; rheumatology; immunology; cardiovascular disease;

    Abstract : Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disorder characterized by inflammation in several organ systems. SLE patients have an impaired ability to clear dying cells which leads to the exposure of several nuclear antigens which might break self tolerance. READ MORE

  3. 3. The PD-1 pathway and the complement system in systemic lupus erythematosus

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Helga Kristjánsdóttir; Marta E Alarcón-Riquelme; Kristján Steinsson; Tom W J Huizinga; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; SLE; autoimmune diseases; PD-1; C4AQ0; low MBL; multicase family; NATURAL SCIENCES Biology Cell and molecular biology Immunology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Immunologi; medicinsk genetik; Medical Genetics;

    Abstract : Autoimmune diseases occur in up to 3-5% of the general population and represent a diverse collection of diseases with regards to clinical manifestations. The unifying factor of autoimmune diseases is tissue and organ damage as a result of an immune response mounted against self-antigens. READ MORE

  4. 4. Insights into the processes preceding the onset of rheumatoid arthritis

    University dissertation from Umeå : Umeå University

    Author : Linda Johansson; Solbritt Rantapää Dahlqvist; Mikael Brink; Felipe Andrade; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; pre-symptomatic individuals; autoantibodies; anti-citrullinated protein peptides antibodies; Epstein-barr virus; neutrophil extracellular traps; periodontitis; Porphyromonas gingivalis; receptor activator of nuclear factor kappa-B ligand; reumatologi; rheumatology;

    Abstract : Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by the production of anti-citrullinated protein antibodies (ACPA) in the majority of all patients and a persistent inflammation in the synovial tissue leading to joint destruction. The aetiology of RA remains to a large extent unknown but is believed to be a complex interplay between genetic, environmental and stochastic factors. READ MORE

  5. 5. On diet in ankylosing spondylitis

    University dissertation from Umeå : Umeå universitet

    Author : Björn Sundström; Solveig Wållberg-Jonsson; Gunnar Johansson; Margaretha Haugen; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diet; ankylosing spondylitits; omega-3; cardiovascular; reumatologi; rheumatology;

    Abstract : The aim of this thesis was to examine the role of diet in ankylosing spondylitis (AS). Patients were examined in: i) a postal questionnaire survey of dietary habits and gastrointestinal (GI) symptoms; ii) a study on biomarkers of diet and disease activity; iii) a comparison of cardiovascular risk factors with the general population using data from the Västerbotten Intervention Programme (VIP), and; iv) a 21-week omega-3 fatty acid supplementation study regarding the effects on disease activity. READ MORE