Search for dissertations about: "rhodopsin"

Showing result 1 - 5 of 28 swedish dissertations containing the word rhodopsin.

  2. 1. Time Resolved Diffraction Studies of Structural Changes in Sensory Rhodopsin

    Author : Robert Bosman; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Rhodopsin; SRII; SRII-HtrII; Time-resolved crystallography; Time-resolved wide angle x-ray scattering; TR-X; TR-WAXS; Serial crystallography;

    Abstract : Responding to different light conditions is an essential process for many organisms on earth. Unicellular organisms are no exception to this and mechanisms for controlling cellular movement must often be sensitive to light. READ MORE

  4. 2. Phenotypes and genotypes in families with hereditary tapetoretinal degenerations

    Author : Vesna Ponjavic; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peripherin.; rhodopsin; cone-rod dystrophy; retinitis pigmentosa; choroideremia; central areolar choroidal dystrophy; mutation screening; full-field electroretinography; Phenotype; genotype; Ophtalmology; Oftalmologi;

    Abstract : The purpose of the study was to characterise the phenotype with emphasis on electroretinography in four different types of hereditary retinal degeneration and to correlate it to a genotype when possible. Two methods were used: full-field electroretinography for objective assessment of retinal function and mutation screening of blood samples for detection of gene alterations. READ MORE

  5. 3. Shedding light on retinal. A contribution to the understanding of the primary process of vision

    Author : Fredrik Blomgren; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; retinal; rhodopsin; quantum mechanics molecular mechanics; calculations; ab initio;

    Abstract : In our eyes light is absorbed by a polyene molecule called retinal. This molecule contains six double bonds and is bonded to a protein. The protein-chromophore complex is called rhodopsin and has been structurally determined by crystallography. It was early suggested that the main event in vision is a cis-trans isomerization of retinal. READ MORE

  6. 4. Identification, Characterization and Evolution of Membrane-bound Proteins

    Author : Pär J. Höglund; Helgi B. Schiöth; Robert Fredriksson; Gert Vriend; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; G protein-coupled receptor; GPCR; Solute Carriers; SLC; Bioinformatics; Evolution; Rhodopsin; Adhesion; Phylogeny; Pharmacology; Farmakologi;

    Abstract : Membrane proteins constitute approximately 30% of all genes in the human genome and two large families of membrane proteins are G protein-coupled receptors (GPCRs) and Solute Carriers (SLCs) with about 800 and 380 human genes, respectively.In Papers I, II and IV, we report 16 novel human Adhesion GPCRs found by searches in NCBI and Celera databases. READ MORE

  7. 5. G Protein-Coupled Receptors; Discovery of New Human Members and Analyses of the Entire Repertoires in Human, Mouse and Rat

    Author : David E. Gloriam; Helgi Schiöth; Robert Fredriksson; Darren Flower; Uppsala universitet; []
    Keywords : Bioinformatics; G protein-coupled receptor; GPCR; Bioinformatics; Evolution; Orphan; Rhodopsin; Adhesion; Phylogeny; Bioinformatik;

    Abstract : G protein-coupled receptors (GPCRs) are signal mediators that have a prominent role in the regulation of physiological processes and they make up the targets for 30-45% of all drugs. Papers I and II describe the discovery of new human GPCRs belonging to the Rhodopsin family, a family which contains many common drug targets. READ MORE