Search for dissertations about: "ribosomal protein genes"

Showing result 1 - 5 of 45 swedish dissertations containing the words ribosomal protein genes.

2. 1. Non-protein-coding RNA : Transcription and regulation of ribosomal RNA

   Author : Stefanie Böhm; Ann-Kristin Östlund Farrants; Brian McStay; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; ribosomal RNA; non-coding RNA; ribosomal genes; rDNA gene; B-WICH; chromatin remodelling; histone modification; Cell Biology; cellbiologi;

   Abstract : Cell growth and proliferation are processes in the cell that must be tightly regulated. Transcription of ribosomal RNA and ribosomal biogenesis are directly linked to cell growth and proliferation, since the ribosomal RNA encodes for the majority of transcription in a cell and ribosomal biogenesis influences directly the number of proteins that are synthesized. READ MORE

4. 2. Ribosomal Proteins in Diamond-Blackfan Anemia : Insights into Failure of Ribosome Function

   Author : Jitendra Badhai; Niklas Dahl; Anthony Wright; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diamond-Blackfan anemia; RPS19; Ribosomal proteins; Haploinsufficiency; cell cycle; Apoptosis; Erythropoiesis; Medical genetics; Medicinsk genetik; Clinical Genetics; klinisk genetik;

   Abstract : Diamond-Blackfan anemia (DBA) is a severe congenital anemia characterized by a defect in red blood cell production. The disease is associated with growth retardation, malformations, a predisposition for malignant disease and heterozygous mutations in either of the ribosomal protein (RP) genes RPS7, RPS17, RPS19, RPS24, RPL5, RPL11 and RPL35a. READ MORE

5. 3. High-resolution phenotypic profiling of a eukaryotic ribosome

   Author : Jonathan Esguerra; Göteborgs universitet; []
   Keywords : ribosome; ribosomal protein genes; box C D snoRNA; box H ACA snoRNA; 2’-O-ribose methylation; pseudouridylation; high-resolution phenotypic profiling; chemogenetic profiling; Saccharomyces cerevisiae; rRNA modification;

   Abstract : All living cells contain ribosomes, complex macromolecular assemblies of ribonucleic acid (RNA) and proteins, responsible for synthesizing polypeptides in a process called translation. High-resolution three-dimensional ribosomal structures coupled with biochemical studies have paved the way in understanding the various mechanistic events during protein synthesis. READ MORE

6. 4. General stress proteins: Novel function and signals for induction of stationary phase genes in E.coli

   Author : Örjan Persson; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; general stress response; universal stress protein; sigma S; DNA damage; fructose-6-phosphate; ruvC;

   Abstract : Survival during conditions when nutrients become scarce requires adaptation and expression of genes for maintenance in order for the cell to survive. Among the numerous proteins involved in adaptation and regulation under these conditions, the stationary phase sigma factor, σS, and the Universal stress proteins contribute to survival and bestow the cell with general stress protective functions during growth arrest. READ MORE

7. 5. The Epstein-Barr nuclear antigens 1 & 5; Study of virus-host cellular protein interactions

   Author : Alma Forsman; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr virus; EBNA1; EBNA5; EBNA-LP; cellular network; virus-host protein interactions;

   Abstract : The Epstein-Barr virus (EBV) is the causative agent or cofactor in the aetiology of several human malignancies such as Burkitt’s lymphoma, Hodgkin’s disease, nasopharyngeal carcinoma (NPC) and lymphoproliferative disorder in immunocompromised patients. EBV is a lymphotropic γ-herpes virus infecting more than 90 percent of the population worldwide. READ MORE