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Showing result 1 - 5 of 182 swedish dissertations matching the above criteria.

2. 1. Removal and Replacement of Ribosomal Proteins : Effects on Bacterial Fitness and Ribosome Function

   Author : Christina Tobin; Dan I. Andersson; Richard Buckingham; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ribosome; protein synthesis; ribosomal proteins; translation initiation; ribosome biogenesis; fitness costs; compensatory evolution; horizontal gene transfer; Microbiology; Mikrobiologi; Biochemistry; Biokemi; Mikrobiologi; Microbiology;

   Abstract : Protein synthesis is a complex process performed by sophisticated cellular particles known as ribosomes. Although RNA constitutes the major structural and functional component, ribosomes from all kingdoms contain an extensive array of proteins with largely undefined functional roles. READ MORE

4. 2. Eukaryotic Ribosome Biogenesis : Focus on the function of the assembly factor Mrd1p

   Author : Åsa Segerstolpe; Lars Wieslander; Susan Gerbi; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome biogenesis; nucleolus; pre-rRNA processing; RNA-binding proteins; Mrd1; Molecular Biology; molekylärbiologi;

   Abstract : The ribosome, the protein factory of the cell, is essential for all life forms. The ribosome is a large RNA-protein machine. It is built in a complex, multi-step process that involves a large number of accessory trans-acting factors and the synthesis consumes a considerable part of the cellular energy. READ MORE

5. 3. Nucleolar Ribosome Assembly

   Author : Fredrik Lackmann; Lars Wieslander; Denis Lafontaine; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome biogenesis; RNA; Nucleolus; Molecular Biology; molekylärbiologi;

   Abstract : Ribosomes are macromolecular machines that are responsible for production of every protein in a living cell. Yet we do not know the details about how these machines are formed. The ribosome consists of four RNA strands and roughly 80 proteins that associate with each other in the nucleolus and form pre-ribosomal complexes. READ MORE

6. 4. The Protein Traffic on the Ribosome : The Mechanism and Regulation of Protein Synthesis in Prokaryotes

   Author : Andrey Zavialov; Måns Ehrenber; Venki Ramakrishnan; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; yellow; ribosome; translation; Gagarin; nobel prize; Biokemi; Biochemistry; Biokemi;

   Abstract : The aim of this work was to understand the molecular mechanism of translation and the mechanism of translation termination, in particular. Cleavage of peptidyl-tRNA and peptide release terminates translation of mRNA on the ribosome. In prokaryotes, three release factors (RFs) are involved in this process. READ MORE

7. 5. The eukaryotic ribosome : a chemical and enzymatic footprinting analysis of the structure and function of ribosomal RNA

   Author : Lovisa Holmberg; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES;

   Abstract : .... READ MORE