Search for dissertations about: "ribosome"

Showing result 16 - 20 of 182 swedish dissertations containing the word ribosome.

  2. 16. The importance of maturation factors in 30S ribosomal subunit assembly

    Author : Stefan Nord; Mikael Wikström; Dan Andersson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome; 30S; rRNA; RimP; RbfA; C23U; rpsE; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The assembly of the ribosome is a complex process that needs to be highly efficient to support maximum growth. Although the individual subunits of the ribosome can be reconstituted in vitro, such a reaction is inefficient in comparison to the assembly rate in vivo. READ MORE

  4. 17. Characterizing Elongation of Protein Synthesis and Fusidic Acid Resistance in Bacteria

    Author : Srihari Nagendra Ravi Kiran Koripella; Suparna Sanyal; Daniel Wilson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome; Elongation factor-G; FusB; GTP; Staphylococcus aureus; Escherichia coli and Fusidic acid; Molecular Biology; Molekylärbiologi;

    Abstract : Protein synthesis is a highly complex process executed by the ribosome in coordination with mRNA, tRNAs and translational protein factors. Several antibiotics are known to inhibit bacterial protein synthesis by either targeting the ribosome or the proteins factors involved in translation. READ MORE

  5. 18. Elongation factor 2: A key component of the translation machinery in eukaryotes : Properties of yeast elongation factor 2 studied in vivo

    Author : Galyna Bartish; Odd Nygård; Suparna Sanyal; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Elongation factor 2; yeast; ribosome; phosphorylation; Switch I; site-directed mutagenesis; functional complementation; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Abstract : Synthesis of proteins is performed by the ribosome, a large ribonucleoprotein complex. Apart from the ribosome, numerous protein factors participate in this process. Elongation factor 2 (eEF2) is one of these factors. eEF2 is an essential protein with a mol. READ MORE

  6. 19. Accuracy of protein synthesis and its tuning by mRNA modifications

    Author : Gabriele Indrisiunaite; Måns Ehrenberg; Suparna Sanyal; Jaanus Remme; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome; Protein synthesis; Translation; Accuracy; Release factor; Termination; mRNA modifications; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : The ribosome is a large macromolecular complex that synthesizes all proteins in the cell in all kingdoms of life. Proteins perform many vital functions, ranging from catalysis of biochemical reactions to muscle movement. It is essential for cells and organisms that proteins are synthesized rapidly and accurately. READ MORE

  7. 20. Computer simulations of ribosome reactions

    Author : Stefan Trobro; Johan Åqvist; Arieh Warshel; Uppsala universitet; []
    Keywords : Molecular biology; ribosomal termination; Empirical valence bond; peptidyl transfer; Molekylärbiologi;

    Abstract : Peptide bond formation and translational termination on the ribosome have been simulated by molecular mechanics, free energy perturbation, empirical valence bond (MD/FEP/EVB) and automated docking methods. Recent X-ray crystallographic data is used here to calculate the entire free energy surface for the system complete with substrates, ribosomal groups, solvent molecules and ions. READ MORE