Search for dissertations about: "ribosomes"

Showing result 21 - 25 of 96 swedish dissertations containing the word ribosomes.

  2. 21. Organization of mitochondrial gene expression in yeast : Specific features of organellar protein synthesis

    Author : Kirsten Kehrein; Martin Ott; Thomas A Fox; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; translation; bc1 complex; ribosome; gene expression; Biochemistry; biokemi;

    Abstract : Mitochondria contain their own genetic system, encoding key subunits of the oxidative phosphorylation system. These subunits are expressed by an organelle-specific gene expression machinery. READ MORE

  4. 22. Mitochondrial Energy Metabolism : Kgd4 is a novel subunit of the α-ketoglutarate dehydrogenase complex

    Author : Manfred Heublein; Martin Ott; Flavia Fontanesi; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; α-ketoglutarate dehydrogenase; Kgd4; Krebs cycle; Biochemistry; biokemi;

    Abstract : Mitochondria are essential organelles of eukaryotic cells and are responsible for their energy metabolism. The citric acid cycle, a chain of redox reactions in the mitochondrial matrix, is a central metabolic hub. READ MORE

  5. 23. Adaptive Evolution of the Bacterial Translation Machinery

    Author : Arindam De Tarafder; Suparna Sanyal; Michael Y. Pavlov; Ruben L. Jr. Gonzalez; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome; Translation; Translation machinery; Elongation; Evolution; RNA world; Cold bacteria; Molekylär biovetenskap; Molecular Life Sciences;

    Abstract : The process of protein synthesis via translation is of paramount importance for the existence of life on Earth. The bacterial translation machinery has embraced more than 3.5 billion years of molecular evolution to adapt and function efficiently under the provided physiological conditions. READ MORE

  6. 24. Dynamics of peptide chains during co-translational translocation, membrane integration & domain folding

    Author : Rickard Hedman; Gunnar von Heijne; Daniel N. Wilson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ribosome; membrane integration; translocation; folding; arrest peptide; SecM; Biochemistry; biokemi;

    Abstract : The biosynthesis of proteins occurs at the ribosomes, where amino acids are linked together into linear chains. Nascent protein chains may undergo several different processes during their synthesis. Some proteins begin to fold, while others interact with chaperones, targeting factors or processing enzymes. READ MORE

  7. 25. Finding the unknowns in trans-translation

    Author : Natalia Ivanova; Måns Ehrenberg; Nenad Ban; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; trans-translation; tmRNA; SmpB; kinetics; footprinting; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : Ribosomes stalled on problematic mRNAs can be rescued by a mechanism called trans-translation. This mechanism employs a dual transfer-messenger RNA molecule (tmRNA) together with a helper protein (SmpB). In this work we have used an in vitro translation system with pure components to further clarify the roles of tmRNA and SmpB in trans-translation. READ MORE