Search for dissertations about: "rickets"

Showing result 1 - 5 of 8 swedish dissertations containing the word rickets.

  2. 1. Biophysical and chemical studies on the epiphysial plate : with special reference to experimental rickets

    Author : Sven-Olof Hjertquist; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  4. 2. The Role of Fibroblast Growth Factor 23 in Phosphate Homeostasis

    Author : Tobias Erik Martin Larsson; Kenneth Jonsson; Östen Ljunggren; Suzanne Jan De Beur; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Fibroblast Growth Factor 23; FGF-23; phosphate homeostasis; vitamin D metabolism; sodium phosphate cotransporters; autosomal dominant hypophosphatemic rickets; ADHR; X-linked hypophosphatemic rickets; XLH; oncogenic osteomalacia; OOM; PHEX; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Abstract : The regulation of serum phosphate (Pi) concentrations is a complex process and our current models are far from complete. Due to major advancements in biotechnology and the development of more powerful research tools, recent advances in the field of genetics has led to the identification of several candidates for the long sought-after phosphatonin(s), or Pi regulating hormones. READ MORE

  5. 3. Studies on the phenotype and function of osteoclasts using osteopetrotic and rachitic animal models

    Author : Karin Hollberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bone mineralization; bone resorption; osteoclast; tartrate-resistant acid phosphatase; proteolytic processing; cathepsin K; rickets; osteopetrosis; FGF-23;

    Abstract : Osteoclasts are multinucleated bone-resorbing cells that have been implicated in a variety of skeletal diseases e.g. osteoporosis, rheumatoid arthritis and skeletal metastasis. Under physiological conditions, the osteoclast participates in ossification during longitudinal bone growth as well as in bone remodelling during adulthood. READ MORE

  6. 4. Matrix resorption in endochondral bone growth : ultrastructural studies, with special attention to the chondroclast

    Author : Joakim Nordahl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : chondroclast; osteoclast; cartilage resorption; TRAP; cathepsin K; fibronectin; bone sialoprotein; osteopontin;

    Abstract : A substantial amount of the calcified cartilage in the distal parts of the epiphyseal plate is resorbed during endochondral growth of long bones. However, the mechanisms involved in this process are still largely unknown. On the other hand, bone-resorption in the lower metaphysis has been thoroughly investigated. READ MORE

  7. 5. Necrotizing enterocolitis - growth, bone health and intestinal microbiota during childhood

    Author : Amanda Magnusson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NEC; Prematur; Benhälsa; Tillväxt; Tarmflora;

    Abstract : Necrotizing enterocolitis (NEC) is a dreaded gastrointestinal disease primarily affecting infants born preterm. Despite extensive research, NEC is still one of the most devastating diseases in neonatal intensive care. READ MORE