Search for dissertations about: "rivastigmine"

Showing result 1 - 5 of 7 swedish dissertations containing the word rivastigmine.

  2. 1. Functional brain activity in Alzheimer patients as studied by multi-tracer positron emission tomography : effects of treatment with cholinesterase inhibitors

    Author : Ahmadul Kadir; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alzheimer’s disease; cholinesterase inhibitors; positron emission tomography; nicotinic acetylcholine receptor; acetylcholinesterase; multi-tracer; 11C-nicotine; 11C-PMP; 18F-FDG; 11C-PIB; donepezil; rivastigmine; galantamine; phenserine.;

    Abstract : Alzheimer’s disease (AD) is a progressive neurodegenerative disease accompanied by cognitive impairment and disturbances in several neurotransmitter systems, especially the cholinergic system. Studies have correlated the cognitive impairment observed in AD patients with a deficit in central cholinergic neurotransmission. READ MORE

  4. 2. Long Term Outcome and Prediction Models of Cognition, Activities of Daily Living and Nursing Home Placement in Alzheimer’s Disease with Cholinesterase Inhibitor Treatment

    Author : Carina Wattmo; Klinisk minnesforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; longitudinal studies; nursing home placement; activities of daily living; cognition; Alzheimer s disease; cholinesterase inhibitors; disease progression; predictors; statistical models.;

    Abstract : Background Prospective longitudinal studies in Alzheimer's disease (AD) that include cholinesterase inhibitor (ChEI) treatment in routine clinical settings are scarce. The patients vary in severity of the disease, clinical course, rate of progression and response to treatment. READ MORE

  5. 3. Pharmacological and environmental modulations of the rat glutamatergic system

    Author : Josefine Andin; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Glutamate is the principal excitatory neurotransmitter in the central nervous system and it is implicated in neural transmission, learning, memory processes and neuronal plasticity. In the glutamatergic synapse two main components are present; the glutamate receptors and the glutamate transporters. READ MORE

  6. 4. Amine Transaminases in Multi-Step One-Pot Reactions

    Author : Mattias Anderson; Per Berglund; Frank Hollmann; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biocatalysis; enzyme; amine transaminase; ω-transaminase; amination; primary amine; chiral amine; chemoenzymatic; green chemistry; synthesis; cascade; Bioteknologi; Biotechnology;

    Abstract : Amine transaminases are enzymes that catalyze the mild and selective formation of primary amines, which are useful building blocks for biologically active compounds and natural products. In order to make the production of these kinds of compounds more efficient from both a practical and an environmental point of view, amine transaminases were incorporated into multi-step one-pot reactions. READ MORE

  7. 5. Long-term treatment response, predictors and biochemical markers in Alzheimer’s disease

    Author : Åsa Wallin; Klinisk minnesforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; treatment response; cholinesterase inhibitor; CSF-biomarkers; pre-treatment progression; predictors; Alzheimer’s disease;

    Abstract : Alzheimer’s disease (AD) is clinically characterised by an insidious onset with progressive symptoms of memory impairment, dysphasia, dyspraxia, dygnosia and visuospatial difficulties. Degeneration of neurons in specific regions of the brain, formation of senile plaques and neurofibrillary changes are some of the neuropathological features of the disease. READ MORE