Search for dissertations about: "rosetting"

Showing result 1 - 5 of 18 swedish dissertations containing the word rosetting.

  2. 1. Antigenic variation in relapsing fever Borrelia

    Author : Nils Burman; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Borrelia; Relapsing fever; Antigenic variation; Vmp lipoprotein; Rosetting;

    Abstract : The spirochete Borrelia hermsii avoids the immune response of its mammalian host through multiphasic antigenic variation. Serotype specificity is determined by Variable major proteins (Vmp), in the outer membrane. READ MORE

  4. 2. Endothelial cytoadherence, rosetting and virulence in Plasmodium falciparum malaria

    Author : Andreas Heddini; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Plasmodium falciparum; malaria; endothelial adhesion; erythrocyte rosetting; PECAM- 1 CID3 1; immunoglobulins; cerebral malaria; PfEMP- 1; var-genes;

    Abstract : Excessive sequestration of Plasmodium falciparum-infected erythrocytes (pRBC) and uninfected erythrocytes directly blocks the microcirculation and precipitates severe symptoms from the affected organ and is thereby thought to be responsible for the severe complications which may occur during P. falciparum infection. READ MORE

  5. 3. Virulence in Plasmodium falciparum malaria : mechanisms of PfEMP1-mediated rosetting

    Author : Davide Angeletti; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Malaria is one of the most important infectious diseases in the world and the Plasmodium falciparum parasite is the causative agent of most of the severe cases. The pathogenesis of the disease is complex but sequestration and hence microvascular obstruction is associated with virulence of the parasite. READ MORE

  6. 4. Host cell adhesion of Plasmodium falciparum-infected erythrocytes

    Author : Carl Johan Treutiger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Plasmodium falciparum; erythrocyte rosetting; cytoadherence; cerebral malaria; PfEMPI; serum proteins; PECAM-I CD31;

    Abstract : Excessive binding of Plasmodium falciparum-infected erythrocytes to the microvascular endothelium (cytoadherence) and to uninfected eryrthrocytes (rosetting) are regarded as key-events in the development of a severe malaria infection. P. falciparum rosetting was confirmed to be associated with the development of cerebral malaria in The Gambia. READ MORE

  7. 5. Immunoglobulins in the adhesion of Plasmodium falciparum-infected erythrocytes in malaria

    Author : Carin Scholander; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Plasmodium falciparum; rosetting; cytoodhesion; immunoglobulins; serum proteins; fibrillar structures; malarial anaemia; placental malaria; PfEMP1;

    Abstract : Characterisation of the delicate cell-to-cell interactions involved in the binding of Plasmodium falciparum- infected erythrocytes to host cells is central for the understanding of the development of severe malaria. Infected erythrocytes adhere in the deep vasculature of several organs, sequestration, leading to cerebral malaria, pulmonary oedema or renal failure. READ MORE