Search for dissertations about: "rpoS"

Showing result 1 - 5 of 12 swedish dissertations containing the word rpoS.

  2. 1. The Physiological Cost of Antibiotic Resistance

    Author : Mirjana Macvanin; Diarmaid Hughes; Stanley Maloy; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; fusidic acid; fitness cost; protein synthesis; EF-G; ppGpp; RpoS; oxidative stress; heme; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Abstract : Becoming antibiotic resistant is often associated with fitness costs for the resistant bacteria. This is seen as a loss of competitiveness against the antibiotic-sensitive wild-type in an antibiotic-free environment. READ MORE

  4. 2. Genetics and Growth Regulation in Salmonella enterica

    Author : Jessica M. Bergman; Diarmaid Hughes; Dan I. Andersson; Måns Ehrenberg; Stanley Maloy; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tufA; tufB; EF-Tu; ppGpp; Stringent response; RNase E; RNA turnover; Post-transcriptional regulation; rpoB; rpoS; Growth in stationary phase; Biology with specialization in Microbiology; Biologi med inriktning mot mikrobiologi; Mikrobiologi; Microbiology; Molekylär genetik; Molecular Genetics; Biology with specialization in Molecular Evolution; Biologi med inriktning mot molekylär evolution;

    Abstract : Most free-living bacteria will encounter different environments and it is therefore critical to be able to rapidly adjust to new growth conditions in order to be competitively successful. Responding to changes requires efficient gene regulation in terms of transcription, RNA stability, translation and post-translational modifications. READ MORE

  5. 3. Too close for comfort : The role of Contact-Dependent growth Inhibition (CDI) in interbacterial competition and cooperation

    Author : Marcus Wäneskog; Sanna Koskiniemi; Paul Rainey; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bacterial interactions; cell-cell binding; contact-dependent growth inhibition; CDI; CdiB; CdiA; CdiI; outer-membrane receptor; BamA; OmpC; OmpF; extracellular toxin delivery; Toxin-Antitoxin; TA-system; persister cells; stress tolerance; stress response; rpoS; rssB; quorum sensing; multicellular behavior; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Contact-Dependent growth inhibition (CDI) was discovered in 2005 in the E. coli isolate EC93. Since then our knowledge of CDI systems and their impact on bacterial communities have increased exponentially. READ MORE

  6. 4. Growth in Aging Colonies : The Importance of Being Different

    Author : Marie Wrande; Diarmaid Hughes; Måns Ehrenberg; Mikael Rhen; Uppsala universitet; []
    Keywords : ;

    Abstract : The accumulation of rifampicin resistant (RifR) mutants in aging bacterial colonies has previously been attributed to stress-induced mutagenesis. Mutations giving rise to RifR are located in the rpoB gene, coding for the β subunit of RNA polymerase, RpoB. READ MORE

  7. 5. Dynamics of the Bacterial Genome : Rates and Mechanisms of Mutation

    Author : Sanna Koskiniemi; Dan Andersson; Diarmaid Hughes; Ivan Matic; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteria; bacterial evolution; genome reduction; gene loss; serial passage; DNA homology; tranlesion DNA polymerase; stress; Microbiology; Mikrobiologi; Bacteriology; Bakteriologi; Evolutionary Genetics; Evolutionär genetik; Mikrobiologi; Microbiology;

    Abstract : Bacterial chromosomes are highly dynamic, continuously changing with respect to gene content and size via a number of processes, including deletions that result in gene loss. How deletions form and at what rates has been the focus of this thesis. In paper II we investigated how chromosomal location affects chromosomal deletion rates in S. READ MORE