Search for dissertations about: "sabrina büttner"
Found 4 swedish dissertations containing the words sabrina büttner.
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1. Metal homeostasis as critical determinant for cellular fitness
Abstract : Metals play a crucial role in cellular biology. Bulk and trace metals such as calcium and manganese regulate a plethora of cellular processes ranging from signaling and oxidative stress to proteostasis and energy metabolism. READ MORE
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2. Cellular remodeling in response to nutrient exhaustion : From membrane contact sites to autophagy
Abstract : Adaptation to fluctuating environments is critical for cellular fitness and survival. Cells need to sense changes in their surroundings and quickly adjust cellular homeostasis and metabolism accordingly. READ MORE
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3. Interorganellar connectivity : From protein to lipid homeostasis
Abstract : Interorganellar connectivity is fundamental for the maintenance of organellar and cellular functionality and viability. This is achieved and maintained by a complex network of signaling cascades, vesicle trafficking between organelles as well as by establishment of direct physical contact at membrane contact sites (MCS). READ MORE
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4. A molecular chaperone that governs membrane contact sites and lipid metabolism
Abstract : Transmembrane proteins represent almost one third of the total cellular proteome, and the majority of them requires translocation into the endoplasmic reticulum (ER) to be folded, sorted and transported to their final subcellular destination. High translational rates during exponential cell growth result in a massive influx of immature proteins into the ER, requiring rapid and accurate folding. READ MORE