Search for dissertations about: "sample size"
Showing result 11 - 15 of 621 swedish dissertations containing the words sample size.
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11. Finding fitness : empirical and theoretical explorations of inferring fitness effects from population-level SNP data
Abstract : The distribution of fitness effects (DFE) describes the likelihood that a new mutation has a specific effect on the fitness of an individual in a given population. The shape of the DFE is a result of several factors such as population size, mating system and selective environment, and can in turn influence the evolutionary potential of a species. READ MORE
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12. Model-Based Optimization of Clinical Trial Designs
Abstract : General attrition rates in drug development pipeline have been recognized as a necessity to shift gears towards new methodologies that allow earlier and correct decisions, and the optimal use of all information accrued throughout the process. The quantitative science of pharmacometrics using pharmacokinetic-pharmacodynamic models was identified as one of the strategies core to this renaissance. READ MORE
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13. Longitudinal Models for Quantifying Disease and Therapeutic Response in Multiple Sclerosis
Abstract : Treatment of patients with multiple sclerosis (MS) and development of new therapies have been challenging due to the disease complexity and slow progression, and the limited sensitivity of available clinical outcomes. Modeling and simulation has become an increasingly important component in drug development and in post-marketing optimization of use of medication. READ MORE
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14. Comparative morphological studies of fossil and living plane trees (Platanaceae) and oaks (Quercus): taxonomy, ecology, evolution
Abstract : Morphological characters are essential for flowering plant identification, but also provide information about diversity patterns and ecological adaptation. In woody plant species, characters of the leaf are among the most useful and can be examined on fossils as well. READ MORE
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15. Fundamental Studies on Direct Injection Nebulisers for Sample Introduction in ICP Spectrometry : Aerosol Properties, ICP Characteristics and Analytical Performance
Abstract : The performance of different types of nebulisers: Vulkan direct injection nebuliser (Vulkan DIN), direct injection high efficiency nebuliser (DIHEN), microconcentric nebuliser coupled to cyclonic or double pass spray chamber (MCN-C or MCN-DP, respectively) was investigated and compared when used for sample introduction to ICP-MS or ICP-OES. With ICP-OES, in axial viewing mode, intensity distributions across the radius of the plasma (radial intensity profiles) were determined for different spectral lines with Esum 1. READ MORE