Search for dissertations about: "scFv"
Showing result 21 - 25 of 37 swedish dissertations containing the word scFv.
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21. Retargeting of adenovirus vectors. Viral ligands and cellular receptors
Abstract : Gene therapy is one of the newest technologies attempted to treat human cancer. Progress in the field has however been hampered by the lack of efficient and safe vectors. Ideal vectors should specifically transduce desired cells in vivo. This thesis is devoted to the development and evaluation of retargeted adenovirus type 5 (Ad5) vectors. READ MORE
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22. Passive immunization against oral pathogens
Abstract : Dental caries is one of the most common infectious diseases and Streptococcus mutans (S. mutans) is considered to be the main etiological agent of dental caries. S. mutans possesses a variety of virulence factors that enables it to establish and initiate disease. READ MORE
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23. Utilizing Solid Phase Cloning, Surface Display And Epitope Information for Antibody Generation and Characterization
Abstract : Antibodies have become indispensable tools in diagnostics, research and as therapeutics. There are several strategies to generate monoclonal antibodies (mAbs) in order to avoid the drawbacks of polyclonal antibodies (pAbs) for therapeutic use. READ MORE
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24. Genetic re-targeting and de-targeting of adenovirus type 5 in order to create vectors for gene therapy
Abstract : Gene therapy has been considered to be a revolutionary development in medicine, whereby the cause and not the symptoms of the disease would be treated. These expectations have as yet not been realized, mainly due to lack of suitable vectors. READ MORE
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25. Molecular Portraits of Cancer : Discovery of Biomarker Signatures using Affinity Proteomics
Abstract : The use of antibodies as capture molecules in assays is a common practice. By either printing monoclonal single chain fragment variables (scFvs) on a solid support – recombinant antibody microarray – or attaching them to magnetic beads – Global Proteome Survey (GPS) – we can specifically capture and measure target proteins of interest. READ MORE