Search for dissertations about: "scFv"

Showing result 6 - 10 of 37 swedish dissertations containing the word scFv.

  2. 6. The CD40 Receptor - Target,Tool and Technology

    Author : Peter Ellmark; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; serology; transplantation; Immunologi; serologi; SPIRE; mammalian; library; cDNA; selection; receptor revision; phage display; scFv; human; CD40; antibodies;

    Abstract : CD40 is a cell surface receptor of pivotal importance that is expressed on several of the cells in the immune system. It is critical for many important events, such as T cell dependent B cell activation, isotype switching, somatic mutation and generation of B cell memory. READ MORE

  4. 7. Biomimetic cell membranes: Lipid-based surface-modifications towards the construction of membrane-protein arrays

    Author : Indriati Pfeiffer; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; qcm-d; protein arrays; DNA tagged-cholesterol; vesicle; scfv; flourescent microscopy; supported phospholipid bilayer;

    Abstract : .... READ MORE

  5. 8. Protein Microarrays Based on Single Framework Recombinant Antibody Fragments (SINFABS) - Catcher and Carrier - A Crucial Combination

    Author : Cornelia Steinhauer; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; serology; transplantation; Immunologi; serologi; probe; coupling chemistry; solid support; stability; scFv; antibody microarray; protein microarray; Biotechnology; Bioteknik;

    Abstract : Antibody-based microarrays are among the novel class of rapidly evolving proteomic technologies. In recent years, antibody microarrays have emerged as a unique tool for high-throughput protein expression profiling with great promise within biomedicine and a wide range of potential applications, including disease diagnostics and biomarker discovery. READ MORE

  6. 9. Discovery of targets for tumor immunotherapy using phage display technology

    Author : Jesper Tordsson; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; colon cancer; melanoma; tumor immunotherapy; phage display; scFv; Immunologi; serologi; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : This thesis has focused on the development of methods and their applications for the identification of antibodies reactive with tumor associated antigens (TAA). The phage display technology provides a powerful mean to generate antibodies potentially useful for tumor immunotherapy. READ MORE

  7. 10. Preclinical PET imaging of Alzheimer's disease progression

    Author : Xiaotian T. Fang; Stina Syvänen; Dag Sehlin; Lars Lannfelt; Merja Haaparanta-Solin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; transgenic mice; PET; antibody-based tracer; mGluR5; ABP688; di-scFv; amyloid-β;

    Abstract : Amyloid PET imaging with [11C]PIB enabled detection of Aβ for the first time in vivo. However, [11C]PIB is a small molecule that binds only the insoluble Aβ plaque. Rather, the soluble Aβ aggregates are considered the cause of Alzheimer’s disease (AD). READ MORE