Search for dissertations about: "scc"

Showing result 1 - 5 of 110 swedish dissertations containing the word scc.

  1. 1. Cytogenetic abnormalities in Acute Myeloid Leukemia in Sweden. A population based study

    University dissertation from Stam Cells Centrum (SCC)

    Author : Vladimir Lazarevic; Lunds universitet.; Lund University.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AML; karyotype; population-based studies; prognosis; chromosomes; hyperdiploidy;

    Abstract : The impact of cytogenetic findings in AML was analyzed in the large population-based Swedish AML registry. Karyotypic patterns differed by age: t(8;21), inv(16) and t(11q23) were more common in younger patients, whereas loss of 5q, 7q and 17p, monosomal karyotype (MK) and complex karyotype (CK) were more common in older patients. READ MORE

  2. 2. Expression and role of the cytokine tyrosine kinase receptor flt3 in early hematopoiesis

    University dissertation from Jörgen Adolfsson, Stem Cell Laboratory, BMC B10, Klinikg 26, 22184 Lund

    Author : Jörgen Adolfsson; Lunds universitet.; Lund University.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; extracellular fluids; Haematology; flt3; cytokine; Hematopoiesis; stem cells;

    Abstract : Popular Abstract in Swedish Blodet består av olika typer av celler med olika funktioner. De röda blodkropparna transporterar syre till alla delar av kroppen, blodplättar stoppar blödningar och en rad olika vita blodkroppar försvarar oss från olika typer av angrepp från till exempel virus eller bakterier. READ MORE

  3. 3. FGF signaling in specification of hESC-derived definitive endoderm

    University dissertation from Stem Cells and Pancreas Development Biology

    Author : Jacqueline Ameri; Lunds universitet.; Lund University.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Popular Abstract in Swedish Diabetes är en snabbt växande folksjukdom som redan har drabbat 200 miljoner världen runt. Det finns två typer av sjukdomen: typ I samt typ II diabetes. Den förstnämnda drabbar vanligtvis de unga och beror på en s.k. READ MORE

  4. 4. Cellular pathways and molecular regulation of hematopoietic stem cells

    University dissertation from Hematopoietic Stem Cell Laboratory

    Author : Kristina Anderson; Lunds universitet.; Lund University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; β-catenin.; lineage commitment; hematopoietic stem cells; lineage priming; Wnt signaling pathway; biphenotypic cells; PAX5;

    Abstract : Hematopoietic stem cells (HSCs) are defined by their unique properties to self-renew and differentiate into all hematopoietic cell lineages. Residing in the bone marrow (BM), adult HSCs are organized in a hierarchy of cells that differ in their self-renewal and proliferative capacity. READ MORE

  5. 5. Downstream effects of master regulators in two brain diseases

    University dissertation from Hematopoietic Stem Cell Laboratory

    Author : Sebastian Braun; Lunds universitet.; Lund University.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rett syndrome; brain tumor development; gene regulation; neural stem cells; cell of origin; BMI1;

    Abstract : In paper one, we investigated how the pharmacological activation and inhibition of the glucocorticoid system affects lifespan and symptoms in a mouse model for RTT. We performed a long-term drug treatment study with the GR activator corticosterone and the GR inhibitor RU486 under which we measured the lifespan and onset of RTT-like symptoms of male Mecp2-null and female Mecp2 heterozygous mice in comparison to untreated mutant and to treated and untreated wild-type animals. READ MORE