Search for dissertations about: "schiff based"

Showing result 1 - 5 of 7 swedish dissertations containing the words schiff based.

  2. 1. Vaccine strategies based on mycobacterial heat shock protein 65

    Author : Maria Sundbäck; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Mycobacteria; DNA vaccination; Hsp65; T cells; CD8 T cell epitopes;

    Abstract : Mycobacteria can infect macrophages and dendritic cells (DC), where they reside inside the endosomal compartment. The importance of CD4+ T cells in protective immunity against mycobacteria and other intracellular pathogens is well established, and for a long time these cells were thought to be the major defense in controlling an infection. READ MORE

  4. 2. Crystallographic studies of transaldolase : implications for the enzymatic mechanism and the evolution of class I aldolases

    Author : Jia Jia; Karolinska Institutet; Karolinska Institutet; []
    Keywords : transaldolase; aldolase; Schiff-base intermediate; protein crystallography; site directed mutagenesis; catalytic mechanism; circular permutation.;

    Abstract : Transaldolase catalyzes the reversible transfer of a dihydroxyacetone moiety from a ketose donor to an aldose acceptor by forming a Schiff-base intermediate between a Iysine residue and dihydroxyacetone. It belongs to the class I aldolase family. READ MORE

  5. 3. Catalysts for Oxygen Production and Utilization : Closing the Oxygen Cycle: From Biomimetic Oxidation to Artificial Photosynthesis

    Author : Erik Karlsson; Jan-Erling Bäckvall; Björn Åkermark; Jerker Mårtensson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; oxygen; catalytic oxidation; biomimetic oxidation; artificial photosynthesis; water oxidation; DFT calculations; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : This thesis describes the development and study of catalysts for redox reactions, which either utilize oxygen or hydrogen peroxide for the purpose of selectively oxidizing organic substrates, or produce oxygen as the necessary byproduct in the production of hydrogen by artificial photosynthesis.The first chapter gives a general introduction about the use of environmentally friendly oxidants in the field of organic synthesis, and about the field of artificial photosynthesis. READ MORE

  6. 4. Computational Design of Molecular Motors and Excited-State Studies of Organic Chromophores

    Author : Baswanth Oruganti; Bo Durbeej; Aurélie Perrier; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : This thesis presents computational quantum chemical studies of molecular motors and excited electronic states of organic chromophores.The first and major part of the thesis is concerned with the design of light-driven rotary molecular motors. READ MORE

  7. 5. Immune and gene therapies for cancer and infectious diseases

    Author : Jehad Charo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Immunotherapy; gene therapy; cytokines; MHC-1; tucaresol; EBV; mycobacteria; HER-2; Tumors;

    Abstract : Annually more than 20 million deaths are globally caused because of infections or cancer. This accounts for 41.5% of annual deaths. New techniques are supposed to constitute our tools in the fight against these types of deaths. READ MORE