Search for dissertations about: "schizoprenia"

Found 3 swedish dissertations containing the word schizoprenia.

  2. 1. Dopachrome and aminochrome, the oxidized metabolites of dopa and dopamine : studies on the molecular mechanisms underlying their reduction and conjugation with glutathione

    Author : Sofia Baez; Francisco Solano Munoz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : Dopamine, like other catecholamines can be oxidized to the corresponding ortho-quinone, which undergoes cyclization of its amino chain to cyclized dopamine ortho-quinone (aminochrome). Both o-quinones are toxic metabolites that may contribute to neurotoxic effects of these catecholamines. READ MORE

  4. 2. Development of radioligands for emission tomography imaging of dopamine D1 and benzodiazepine receptors

    Author : Christian Foged; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Dopamine D1 receptors; Benzodiazepine BZ receptors; PET; SPECT.Stoc;

    Abstract : Brain imaging of dopamine and benzodiazepine (BZ) receptors in vivo is of central interest in neuropsychiatric disorders such as schizoprenia, Huntington's disease and epilepsy. The objective was to develop new radioligands for emission tomography of dopamine D1 and BZ receptors. READ MORE

  5. 3. Neuronal nicotinic receptor subtypes in normal ageing, Alzheimer's disease and schizophrenia : influences of neuropathological mechanisms as studied in human autopsy brain and transgenic mice

    Author : Amelia Marutle; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ageing; Alzheimer s disease; P-amyloid; Nicotinic acetylcholine receptor subtypes; Postmortem human brain; Schizophrenia; Transgenic mice;

    Abstract : Neuronal nicotinic acetylcholine receptors (nAChRs) are transmitter-gated ion channel receptors which are widely distributed in the brain. They mediate the effects of several neurotransmitters including ACh, DA, 5-HT and NA and are important for many normal physiological functions in the brain and are also implicated in a number of CNS disorders, such as AD, PD, schizophrenia, Tourette's syndrome and familial epilepsy. READ MORE