Search for dissertations about: "secondary active transporters"

Showing result 1 - 5 of 6 swedish dissertations containing the words secondary active transporters.

  2. 1. Establishing the molecular mechanism of sodium/proton exchangers

    Author : Povilas Uzdavinys; David Drew; Peter Brzezinski; M.D. Daniel Fuster; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; membrane protein; secondary active transporters; sodium proton exchangers; proton transport; structure; energetics; Biochemistry; biokemi;

    Abstract : Sodium/proton exchangers are ubiquitous secondary active transporters that can be found in all kingdoms of life. These proteins facilitate the transport of protons in exchange for sodium ions to help regulate internal pH, sodium levels, and cell volume. READ MORE

  4. 2. Structure, Mechanism, and Regulation of Sodium/Proton Exchangers

    Author : Iven Winkelmann; Drew David; Rajini Rao; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; sodium proton exchange; SLC9; structure; secondary active transport; membrane protein; Biochemistry; biokemi;

    Abstract : Sodium/proton exchangers (NHEs) are secondary active transporters that are ubiquitously found in all kingdoms of life. They facilitate the exchange of protons for sodium ions or other inorganic ions across biological membranes, regulating pH, sodium levels, and osmotic pressure. READ MORE

  5. 3. Elucidating the molecular basis of Na+/H+ exchange

    Author : Pascal F. Meier; David Drew; Simon Newstead; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; membrane protein; secondary-active transporter; Solute Carrier Transporter; ion-exchange; sodium proton exchanger; potassium proton exchanger; protein structure; cryo-EM; regulation; biokemi; Biochemistry;

    Abstract : Solute carrier (SLC) transporters are membrane transport proteins, which catalyse the movement of nutrients, ions, and drugs across cell membranes. Here, I will present our contribution to understanding the mechanism of the sodium/proton exchangers (NHE), belonging to the SLC9 family of membrane transporters. READ MORE

  6. 4. Structural and functional studies of nutrient and drug uptake systems

    Author : Fatma Guettou; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Orally ingested nutrients and drugs are selectively absorbed from our small intestines into the bloodstream through various membrane-integrated transporters. The present study focuses mainly on a specific absorption route, namely the proton dependent oligopeptide transporters (POTs). READ MORE

  7. 5. Transport of sodium and protons in the human placenta. Mechanisms in normal pregnancy and alterations in intrauterine growth restriction

    Author : Martin Johansson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; placenta; Na K ATPase; Na H exchanger; H K ATPase; intrauterine growth restriction; BeWo cells; epithelial transport;

    Abstract : The syncytiotrophoblast cell of the human placenta represents the interface between maternal and fetal blood supplies. This polarized epithelium consists of a maternal facing microvillous membrane (MVM) opposing a fetal facing basal membrane (BM). This unique syncytial cell is responsible for transfer of all nutrients to the developing fetus. READ MORE