Search for dissertations about: "secondary metabolism"

Showing result 1 - 5 of 100 swedish dissertations containing the words secondary metabolism.

  1. 1. Systems Biology of the Secondary Metabolism in Filamentous Fungi

    University dissertation from ; Chalmers tekniska högskola; Gothenburg

    Author : Jens Christian Froslev Nielsen; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; genomics; systems biology; secondary metabolites; antibiotics; Next-generation sequencing; secondary metabolism; filamentous fungi; cell factories; Penicillium;

    Abstract : Filamentous fungi constitute a rich reservoir of pharmaceutically relevant bioactive small molecules. These compounds, commonly referred to as secondary metabolites, are widely used as antibiotics for the treatment of microbial infections, but also as other pharmaceuticals such as immunosuppressors, cholesterol lowering agents and anticancer drugs. READ MORE

  2. 2. Affinity Two-Phase Partitioning of Liposomes and Membranes

    University dissertation from Department of Biochemistry, Lund University

    Author : Irene Barinaga-Rementeria Ramírez; Lunds universitet.; Lund University.; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; miniaturised two-phase system; levitated drop; biotin; avidin; antibody; immunoaffinity; purification; rat lung; rat liver; caveolae; membrane; Affinity two-phase partitioning; liposome; Metabolism; Biochemistry; Biokemi; metabolism;

    Abstract : Affinity two-phase partitioning based on an immunoaffinity sandwich approach for the rapid and selective purification of membranes is presented in this thesis. The method was developed by studying different parameters governing the affinity partitioning of model membranes. To this end, biotinylated liposomes were used. READ MORE

  3. 3. Vitreoscilla Haemoglobin. Genetic Fusions and Metabolic Characterisation

    University dissertation from Viktoria Roos, Pure & Applied Biochemistry, Lund University

    Author : Viktoria Roos; Lunds universitet.; Lund University.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Metabolism; Biokemi; metabolism; osmotic stress; transcript profiling; DNA microarrays; random elongation mutagenesis; directed evolution; mRNA structure; Vitreoscilla haemoglobin VHb ; Escherichia coli; salt stress.;

    Abstract : Popular Abstract in Swedish Genteknik innebär stora möjligheter att förändra och förbättra organismers egenskaper. Genom att i en organism föra in en främmande gen kan man ge den helt nya egenskaper som den aldrig skulle ha förvärvat på naturlig väg. READ MORE

  4. 4. Protein Folding Studied by Site Directed Mutagenesis

    University dissertation from Tomas Ternström, Avd. f. Biokemi, Lunds universitet

    Author : Tomas Ternström; Lunds universitet.; Lund University.; [2002]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Biokemi; metabolism; Biochemistry; Transition state; Activation Barrier; Two-State; Protein Folding; Protein Engineering;

    Abstract : The N-terminal RNA binding domain of U1A has been shown to fold in a two-state process without accumulating any intermediates. U1A has a symmetrically curved chevron plot which seems to result mainly from changes of the transition state. READ MORE

  5. 5. Isolation of caveolae using affinity two-phase partitioning

    University dissertation from Biochemistry, Center for Chemistry and Chemical Engineering, Lund University

    Author : Parisa Abedinpour; Lunds universitet.; Lund University.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; metabolism; Biokemi; Metabolism; Biochemistry; basolateral; apical; immunoaffinity; wheat germ agglutinin; caveolin; caveolae caveolae enriched fraction; plasma membranes; rat lung; rat liver; Affinity Partitioning; two-phase partitioning;

    Abstract : Popular Abstract in Swedish Målsättningen för detta arbete var att isolera caveolae för att kunna studera deras struktur och funktion. Caveolae är omegaformade inbuktningar i cellmembranet, ungefär 50-150 nm i diameter. Caveolae finns i många typer of celler, men inte i röda och vita blodkroppar eller nervceller. READ MORE