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Showing result 1 - 5 of 124 swedish dissertations matching the above criteria.
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1. Systems Biology of the Secondary Metabolism in Filamentous Fungi
Abstract : Filamentous fungi constitute a rich reservoir of pharmaceutically relevant bioactive small molecules. These compounds, commonly referred to as secondary metabolites, are widely used as antibiotics for the treatment of microbial infections, but also as other pharmaceuticals such as immunosuppressors, cholesterol lowering agents and anticancer drugs. READ MORE
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2. Affinity Two-Phase Partitioning of Liposomes and Membranes
Abstract : Affinity two-phase partitioning based on an immunoaffinity sandwich approach for the rapid and selective purification of membranes is presented in this thesis. The method was developed by studying different parameters governing the affinity partitioning of model membranes. To this end, biotinylated liposomes were used. READ MORE
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3. Vitreoscilla Haemoglobin. Genetic Fusions and Metabolic Characterisation
Abstract : Vitreoscilla is an obligate aerobic bacterium living in oxygen-poor environments such as stagnant ponds and decaying vegetable matter. Vitreoscilla expresses a homodimeric haemoglobin (VHb) when subjected to oxygen-limited conditions. READ MORE
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4. Protein Folding Studied by Site Directed Mutagenesis
Abstract : The N-terminal RNA binding domain of U1A has been shown to fold in a two-state process without accumulating any intermediates. U1A has a symmetrically curved chevron plot which seems to result mainly from changes of the transition state. READ MORE
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5. Isolation of caveolae using affinity two-phase partitioning
Abstract : The intention of this work was to establish alternative purification methods to obtain highly purified caveolae from various tissues. In order to isolate caveolae, sufficiently pure plasma membranes are needed. READ MORE