Search for dissertations about: "secondary metabolism"
Showing result 16 - 20 of 124 swedish dissertations containing the words secondary metabolism.
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16. Neurointensive care of subarachnoid hemorrhage : Clinical and neurochemical aspects
Abstract : Neurointensive care (NIC) has gained terrain in the treatment of patients with various acute cerebral conditions. It is based on the concept that an unfavorable clinical outcome, to a certain extent, results from all secondary ischemic insults sustained by the brain during the acute phase of the disease. READ MORE
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17. Development of Gene Therapy for Hematopoietic Stem Cells using Lentiviral Vectors
Abstract : Hematopoietic stem cells are an ideal target for genetic manipulation for the purpose of curing hematological disorders as they have the ability to develop into all blood lineages and to self-renew. In this study we demonstrate that lentiviral vectors, based on HIV-1, can efficiently transfer genes into human hematopoietic progenitor and stem cells as assessed following stem cell transplantation in immune compromised mice. READ MORE
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18. Glucose and lipid metabolism in insulin resistance : an experimental study in fat cells
Abstract : Type 2 diabetes is usually caused by a combination of pancreatic β-cell failure and insulin resistance in target tissues like liver, muscle and fat. Insulin resistance is characterised by an impaired effect of insulin to reduce hepatic glucose production and to promote glucose uptake in peripheral tissues. READ MORE
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19. An insight into the metabolism of New Psychoactive Substances : Structural elucidation of urinary metabolites of synthetic cannabinoids and fentanyl analogues using synthesized reference standards
Abstract : New Psychoactive Substances (NPS) is an umbrella term covering hundreds of substances across different drug groups. Many of these substances were originally developed for therapeutic use but have later appeared on the recreational drug market. READ MORE
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20. Genomic clues to secondary injury mechanisms in brain trauma
Abstract : Traumatic brain injury (TBI) is a heterogenous disease that can lead to persistent disability or death. The immediate mechanical disruption of brain tissue is followed by a phase of secondary brain injury. During this phase TBI challenges clinical interventions due to its complexity. READ MORE