Search for dissertations about: "secretory granules"

Showing result 1 - 5 of 45 swedish dissertations containing the words secretory granules.

  2. 1. Storage organelles that are distinct from the classical granules in human neutrophils

    Author : Sara Pellmé; Göteborgs universitet; []
    Keywords : neutrophil; HL-60 cells; cytoplasts; granules; CXCL-8; ER; phagocytosis; HLA-I; subcellular fractionation; immunogold;

    Abstract : The human neutrophil is a crucial participant in acute inflammation. Appropriate immune response is dependent on rapid direction of phagocytic cells through the tissue, towards the inflammatory focus. Such movement is governed by chemoattractants, e.g. READ MORE

  4. 2. Sorting and processing of neutrophil granule proteins

    Author : Elinor Bülow; Avdelningen för hematologi och transfusionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; secretion; Haematology; extracellular fluids; Hematologi; extracellulära vätskor; cell-specific retention; chimeric; lysosome-related organelles; secretory pathway; propeptide of MPO; azurophil granules;

    Abstract : The neutrophil granulocytes have a critical role in innate immunity in particular through phagocytosis of microorganisms. Their cytoplasmic granule subsets store digestive enzymes and antibiotic proteins that are released during this event. READ MORE

  5. 3. Induction of Mast Cell Apoptosis via Granule Permeabilization : A Novel Approach to Target Mast Cells

    Author : Aida Paivandy; Gunnar Pejler; Magda Babina; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Granules; Apoptosis; Reactive oxygen species; ROS; Lysosomotropic agents; Mefloquine; Immunologi; Immunology; Biokemi; Biochemistry;

    Abstract : Mast cells are densely granulated tissue-resident immune cells that play an important role in orchestrating inflammatory responses. Dysregulated increases in the numbers and activation status of mast cells can have deleterious consequences for the body in various inflammatory diseases. READ MORE

  6. 4. Mechanisms for Targeting of Proteins to Secretory Lysosomes of Haematopoietic Cells

    Author : Hanna Rosén; Avdelningen för hematologi och transfusionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; Haematology; extracellular fluids; haematopoietic cells; Medicin människa och djur ; Medicine human and vertebrates ; secretory lysosomes; protein targeting;

    Abstract : The cells of the innate immune system are essential for the host's first line defence against infection. Among these cells the neutrophil granulocyte has a central role by the production of antibiotic proteins and peptides. READ MORE

  7. 5. Immunofluorescence Investigation on Neuroendocrine Secretory Protein 55 (NESP55) in Nervous Tissues

    Author : Yongling Li; Göteborgs universitet; []
    Keywords : NESP55; neuropeptdides; chromogranins; the CAD cell line; rat; spinal cord; sympathetic ganglia; retrograde tracing; immunofluorescence; confocal microscopy; secretory pathway;

    Abstract : The chromogranin family is a group of acidic, soluble, and heat-stable proteins widespread in various neuronal, neuroendocrine and endocrine tissues, where they are subcellullarly located in the secretory granules, participating in the formation of the granules. Extracellularly, chromogranins may act as protein precursors, proteolytically processed to various small bioactive peptides. READ MORE