Search for dissertations about: "selective cell lysis. sepsis"

Found 4 swedish dissertations containing the words selective cell lysis. sepsis.

2. 1. Microfluidic bases sample preparation for blood stream infections

   Author : Sahar Ardabili; Aman Russom; Mats Nilsson; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; sample-preparation; microfluidics; sepsis; size-based separation; selective cell-lysis; immune-based isolation; Biotechnology; Bioteknologi;

   Abstract : Microfluidics promises to re-shape the current health-care system by transferring diagnostic tools from central laboratories to close vicinity of the patient (point-of-care). One of the most important operational steps in any diagnostic platform is sample preparation, which is the main subject in this thesis. READ MORE

4. 2. Microfluidic blood sample preparation for rapid sepsis diagnostics

   Author : Jonas Hansson; Hjalmar Brismar; Aman Russom; Fredrik Nikolajeff; KTH; []
   Keywords : 3D fluidic networks; bacteria isolation; inertial microfluidics; lab-on-chip; microfluidics; particle filtration; PDMS membrane; selective cell lysis. sepsis;

   Abstract : Sepsis, commonly referred to as blood poisoning, is a serious medical condition characterized by a whole-body inflammatory state caused by microbial infection. Rapid treatment is crucial, however, traditional culture-based diagnostics usually takes 2-5 days. READ MORE

5. 3. Novel microfluidic based sample preparation methods for rapid separation and detection of viable bacteria from blood for sepsis diagnostics

   Author : Sharath Narayana Iyengar; Aman Russom; Jonas Tegenfeldt; KTH; []
   Keywords : microfluidics; Bioteknologi; Biotechnology;

   Abstract : Sepsis is a serious medical condition characterized by a whole-body inflammatory response caused by bloodstream infection. The final stage of sepsis can lead to septic shock, multiple organ failure, and death. In early sepsis, the concentration of bacteria in the bloodstream is typically low, making diagnosis challenging. READ MORE

6. 4. From Lab to Chip – and back : Polymer microfluidic systems for sample handling in point-of-care diagnostics

   Author : Jonas Hansson; Wouter van der Wijngaart; Hywel Morgan; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Electrical Engineering; Elektro- och systemteknik;

   Abstract : This thesis contributes to the development of Lab-on-a-Chip systems that enables reliable, rapid medical diagnostics at the point-of-care. These contributions are focused on microfluidic Lab-on-a-Chip systems for sepsis diagnosis, autonomous sample-to-answer tests, and dried blood spot sampling. READ MORE