Search for dissertations about: "selective serotonin-reuptake inhibitor SSRI"
Showing result 1 - 5 of 23 swedish dissertations containing the words selective serotonin-reuptake inhibitor SSRI.
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1. On the Effects of Serotonin Reuptake Inhibitors in Major Depression
Abstract : This thesis focuses on the antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) and how these are reflected by the Hamilton Depression Rating Scale (HDRS). To this end, we have assembled a large data set of placebo-controlled SSRI trials in major depression, and used this for a series of post-hoc patient-level analyses. READ MORE
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2. On the efficacy and prescription of serotonin reuptake inhibitors
Abstract : This thesis addresses several controversial issues regarding commonly used antidepressants, including selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs). To this end, patient-level data from 28 placebo-controlled trials on SSRIs and 13 corresponding trials on the SNRI duloxetine, were requested and obtained. READ MORE
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3. Biological Aspects of Peripartum Depression
Abstract : Peripartum depression affects around 12% of women in pregnancy and postpartum, and about 2–3% of European pregnant women use antidepressants, mostly selective serotonin reuptake inhibitors (SSRIs). An increased risk of poor pregnancy outcomes has been described in women with antenatal depression and SSRI treatment during pregnancy. READ MORE
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4. Posttraumatic Stress Disorder (PTSD) in the General Population
Abstract : This thesis explored the epidemiology of Posttraumatic Stress Disorder (PTSD) and different aspects of the disorder. Firstly, we investigated the lifetime prevalence of traumatic experiences and PTSD in the general adult population in Sweden and evaluated the impact of different trauma types, trauma frequency, and perceived distress. READ MORE
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5. Drug repositioning in chemoprevention of colorectal cancer
Abstract : BackgroundColorectal cancer (CRC) ranks as the third most frequently occurring cancer and the second leading cause of cancer-related deaths worldwide. In response to the high demand for an effective prevention strategy, chemoprevention, using medications to block the pathogenetic pathways of disease, might be an attractive strategy to offer a more effective option at a low cost. READ MORE