Search for dissertations about: "self antigens"

Showing result 11 - 15 of 87 swedish dissertations containing the words self antigens.

  2. 11. Diversity of CD1d-restricted natural killer T cells

    Author : Markus Sköld; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; autoreactive; Ly49 receptor; CD1d; NKT cell; transplantation; Immunologi; serologi;

    Abstract : The present study deals with natural killer (NK) T cells restricted to the antigen presenting molecule CD1d. NKT cells have been suggested to play a role in many diverse immunological situations such as clearance of different pathogens, protection against certain tumors, regulation of autoimmune reactions and as a link between innate and adaptive immune responses. READ MORE

  4. 12. Reign in Blood : Immune Regulation in Type 1 Diabetes

    Author : Mikael Pihl; Rosaura Casas; Johnny Ludvigsson; Marianne Quiding-Järbrink; Linköpings universitet; []
    Keywords : ;

    Abstract : Type 1 Diabetes (T1D) is an autoimmune disease resulting in insulin deficiency as a result ofautoimmune destruction of pancreatic β-cells. Preserving β-cell function in patients with T1D would be of great benefit since patients with sustained endogenous insulin secretion are known to suffer less from secondary complications due to hyperglycemia. READ MORE

  5. 13. MHC-class I restricted peptide-based immunomodulation of CD8+ T and NK cells

    Author : Adil Doganay Duru; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The main aims of the immune system are to protect the host from potential threats by distinguishing self from non-self and altered-self. T cells and NK cells play a key role in the identification and elimination of threats by scanning a repertoire of peptide epitopes presented by major histocompatibility complex (MHC) molecules. READ MORE

  6. 14. Studies of cytotoxic T lymphocytes and natural killer cells in relation to MHC class I presented peptides

    Author : Lars Franksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : T-cell; NK cell; MHC class I; peptide;

    Abstract : In the defense against disease it is essential for the immune system to be able to discriminate self/normal from non-self/abnormal. This key feature of the immune system relies on the presentation of antigens by MHC class I and class II molecules. READ MORE

  7. 15. HLA and KIR gene polymorphism in hematopoietic stem cell transplantation

    Author : Marie Schaffer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HLA; KIR; NK cells; hematopoietic stem cell transplantation; unrelated donor;

    Abstract : The major histocompatibility complex (MHC) in humans known as the Human Leukocyte Antigens (HLA) is localised to the short arm of chromosome six. The HLA class 1 antigens, HLA-A, -B and -C are highly polymorphic glycoproteins expressed on the cell surface of most nucleated cells in the body. READ MORE