Search for dissertations about: "sequence database"

Showing result 1 - 5 of 80 swedish dissertations containing the words sequence database.

  2. 1. From Sequence to Structure : Using predicted residue contacts to facilitate template-free protein structure prediction

    Author : Mirco Michel; Arne Elofsson; Erik Lindahl; Johannes Söding; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein bioinformatics; protein structure prediction; contact prediction; machine learning; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Despite the fundamental role of experimental protein structure determination, computational methods are of essential importance to bridge the ever growing gap between available protein sequence and structure data. Common structure prediction methods rely on experimental data, which is not available for about half of the known protein families. READ MORE

  4. 2. Improved Neuropeptide Identification : Bioinformatics and Mass Spectrometry

    Author : Maria Fälth Savitski; Per Andrén; David Fenyö; Per Svenningsson; Ronald Beavis; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; neuropepides; database; peptide identification; peptide fragmentation; mass spectrometry; tandem mass spectromerty; Bioinformatics; Bioinformatik;

    Abstract : Bioinformatic methods were developed for improved identification of endogenous peptides using mass spectrometry. As a framework for these methods, a database for endogenous peptides, SwePep, was created. It was designed for storing information about endogenous peptides including tandem mass spectra. READ MORE

  5. 3. Characterization of protein families, sequence patterns, and functional annotations in large data sets

    Author : Anders Bresell; Bengt Persson; Inge Jonassen; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioinformatics; sequence analysis; patterns; protein families; Bioinformatics; Bioinformatik;

    Abstract : Bioinformatics involves storing, analyzing and making predictions on massive amounts of protein and nucleotide sequence data. The thesis consists of six papers and is focused on proteins. READ MORE

  6. 4. Metagenomic Characterization of the Gut Microbiome in Cohorts of Elderly

    Author : Sukithar K Rajan; Dirk Repsilber; Carl Mårten Lindqvist; Robert Jan Brummer; Lars-Gustav Snipen; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gut microbiota; metagenomics; High-Throughput Nucleotide Sequencing; reference sequence database; methods validation; microbial function; host-microbe interaction;

    Abstract : Human gut microbiota plays a vital role in maintaining host health. This thesis aims to investigate the gut microbial population and function using next generation sequencing (NGS) data from faecal samples. Paper I examines the influence of sequencing depth and analysis methods in microbiota profiling using NGS whole genome sequencing (WGS) data. READ MORE

  7. 5. MRI based radiotherapy planning and pulse sequence optimization

    Author : Jens Sjölund; Hans Knutsson; Mats Andersson; Michael Felsberg; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Radiotherapy plays an increasingly important role in cancer treatment, and medical imaging plays an increasingly important role in radiotherapy. Magnetic resonance imaging (MRI) is poised to be a major component in the development towards more effective radiotherapy treatments with fewer side effects. READ MORE