Search for dissertations about: "sequence identification"

Showing result 21 - 25 of 276 swedish dissertations containing the words sequence identification.

  2. 21. Predicting the route: from protein sequence to sorting in eukaryotic cell

    Author : Marco Salvatore; Arne Elofsson; Norman Davey; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; eukaryotic cell; sorting signals; subcellular localisation; machine learning; biological sequence analysis; bioinformatics; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Proteins need to be localised in the correct compartment of a eukaryotic cell to function correctly. Therefore, a protein needs to be transported to the right location. Specific signals present in the protein sequence direct proteins to different subcellular localisations. READ MORE

  4. 22. Statistical modelling and analyses of DNA sequence data with applications to metagenomics

    Author : Mariana Buongermino Pereira; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; generalised hidden Markov models; gene abundance data; metagenomics; statistical modelling; bioinformatics; normalisation; DNA sequence data; bioinformatics;

    Abstract : Microorganisms are organised in complex communities and are ubiquitous in all ecosystems, including natural environments and inside the human gut. Metagenomics, which is the direct sequencing of DNA from a sample, enables studying the collective genomes of the organisms that are there present. READ MORE

  5. 23. Statistical assessment of somatic mutations and genomic variability using DNA sequence data

    Author : Anna Rehammar; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA sequence data; exome sequencing; calling of somatic mutations; metagenomics; hierarchical Bayesian model; genomic variability; calling of somatic mutations;

    Abstract : The development of new DNA sequencing techniques have made it possible to generate high-resolution genomic data at an unprecedented pace. However, the high dimensionality in combination with the substantial levels of technical errors and biological variability make the analysis challenging. READ MORE

  6. 24. JOINING SEQUENCE OPTIMIZATION IN COMPLIANT VARIATION SIMULATION

    Author : Roham Sadeghi Tabar; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Compliant Variation Simulation; Sequencing; Optimization; Joining;

    Abstract : Disturbances in the manufacturing and assembly processes cause deviation and geometrical variation from the ideal geometry. This variation eventually results in functional and aesthetic problems in the final product. Being able to control the disturbances is the desire of the manufacturing industry. READ MORE

  7. 25. Identification and Characterization of Novel Candidate Oncogenes

    Author : Marina Mencinger; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk genetik; Clinical genetics; RBP56; APRIL; TFG; FUS; EWS; EST database; fusion genes; chromosome; molecular genetics; cancer; Cytology; oncology; cancerology; Cytologi; onkologi;

    Abstract : Using computer-assisted sequence homology searches we identified three genes encoding proteins similar to certain fusion partner proteins in cancer. The novel APRIL gene was localized to 15q25 and encodes a protein, containing an acidic amino-acid region similar to that/those of leukemia-associated fusion partner proteins DEK and SET. READ MORE