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Showing result 11 - 15 of 1406 swedish dissertations matching the above criteria.

  2. 11. Technologies for Single Cell Genome Analysis

    Author : Erik Borgström; Afshin Ahmadian; Sten Linnarsson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA; sequencing; single molecule; single cell; whole genome amplification; exome sequencing; emulsions; barcoding; phasin; Biotechnology; Bioteknologi;

    Abstract : During the last decade high throughput DNA sequencing of single cells has evolved from an idea to one of the most high profile fields of research. Much of this development has been possible due to the dramatic reduction in costs for massively parallel sequencing. READ MORE

  4. 12. Sequencing of genes and genomes

    Author : Fredrik Sterky; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; DNA sequencing; genome analysis; expressed sequence tag; expression analysis; complementary DNA; biotin-capture; solid-phase technology; automation; poplar; Bioengineering; Bioteknik;

    Abstract : .... READ MORE

  5. 13. Breast Cancer Biomarkers with Clinical Relevance Identified by Massively-parallel DNA and RNA Sequencing

    Author : Malin Dahlgren; Translational Oncogenomics; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; DNA sequencing; RNA sequencing; Metastasis; Biomarker; Estrogen receptor alpha; Estrogen receptor beta; ESR1; ESR2; Breast cancer; DNA sequencing; RNA sequencing; metastasis; biomarker; Estrogen receptor alpha; Estrogen receptor beta; ESR1; ESR2;

    Abstract : Women have a 10% lifetime risk of developing breast cancer, and the disease has surpassed lung cancer as the most frequently diagnosed type of cancer in the world. Breast cancer originates in the epithelial cells of the mammary gland and tumor cells have undergone a series of genetic and phenotypic changes that confer tumor promoting properties. READ MORE

  6. 14. Methods to Prepare DNA for Efficient Massive Sequencing

    Author : Sverker Lundin; Joakim Lundeberg; Harold Swerdlow; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA; Massive sequencing; Next Generation Sequencing; Library Preparation; Barcoding; Multiplexing;

    Abstract : Massive sequencing has transformed the field of genome biology due to the continuous introduction and evolution of new methods. In recent years, the technologies available to read through genomes have undergone an unprecedented rate of development in terms of cost-reduction. READ MORE

  7. 15. Genome sequencing. Analysis of pathogenicity factors in hereditary and bacterial diseases

    Author : Joakim Westberg; KTH; []
    Keywords : genome sequencing; DNA sequencing; dye-terminator; solid-phase; de novo mutation detection; Mycoplasma mycoides subsp. mycoides SC; mycoplasma; CBPP; properdin; insertion sequence; ISMmy1;

    Abstract : With a metal removal process based on precipitation aimed atthe purification of pulping effluent as a starting point, theinfluence of carboxylic acids on calcium carbonateprecipitation has been studied. The chosen carboxylic acids canact as more or less strong complexing agents for aqueouscalcium, just as many compounds found in pulping liquors. READ MORE