Search for dissertations about: "serin kinase"

Found 3 swedish dissertations containing the words serin kinase.

  2. 1. Cyclic Nucleotide Phosphodiesterase 3B: Regulation in rat adipocytes and 3T3-L1 cells

    Author : Tova Landström; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3T3-L1 TNF-alpha; adipocyte; insulin; p70S6 kinase; mitogen-activated protein kinase; protein kinase B; phosphatidylinositol-3 kinase; phosphodiesterase 3B; cAMP; lipolysis; phosphorylation; signal transduction; Biochemistry; Metabolism; Biokemi; metabolism;

    Abstract : Insulin stimulation of rat adipocytes results in phosphorylation and activation of the cyclic nucleotide phosphodiesterase 3B (PDE3B), a key enzyme in the antilipolytic signalling pathway of this hormone. In this thesis, the site phosphorylated in PDE3B upon stimulation of rat adipocytes with insulin and/or the beta-adrenergic agonist, isoproterenol is identified. READ MORE

  4. 2. Regulation of PKCalpha and the role of PKC in neuroblastoma cell migration

    Author : Helena Stensman; Institutionen för translationell medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; oncology; cancerology; Cytologi; Medicin människa och djur ; Medicine human and vertebrates ; neuroblastoma; cell migration; intramolecular interactions; autophosphorylation; Protein kinase C; onkologi; cancer;

    Abstract : Members of the protein kinase C (PKC) family of serine/threonine kinases play critical roles in cellular regulation. Depending on differences in regulation, PKCs can be divided into classical (alpha, betaI, betaII and gamma), novel (delta, epsilon, eta and theta) and atypical (zeta and iota/lambda) isoforms. READ MORE

  5. 3. Structure-function relationships of hormone-sensitive lipase

    Author : Torben Österlund; Institutionen för translationell medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteins; mutagenesis; domain; fold; catalytic triad; lipase; structure; enzymology; Proteiner; enzymologi;

    Abstract : The primary role of hormone-sensitive lipase (HSL), an 84 kDa enzyme of 768 amino acids (in the rat protein), is to hydrolyse stored triacylglycerols in adipocytes of white adipose tissue. Catecholamines and insulin regulate lipolysis through cellular signalling. READ MORE