Search for dissertations about: "serine hydrolase"

Showing result 1 - 5 of 8 swedish dissertations containing the words serine hydrolase.

  2. 1. Serine Hydrolase Selectivity : Kinetics and applications in organic and analytical chemistry

    Author : Anders Hamberg; Karl Hult; Dick Janssen; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Candida antarctica lipase B; monoacylation of diols; kinetic resolution; thermodynamics in enzyme catalysis; enzyme engineering; Biochemistry; Biokemi;

    Abstract : The substrate selectivities for different serine hydrolases were utilized in various applications, presented in papers I-VI. The articles are discussed in the thesis in view of the kinetics of the enzyme catalysis involved. READ MORE

  4. 2. Production and engineering of a xyloglucan endo-transglycosylase from Populus tremula x tremuloides

    Author : Maria Henriksson; Tuula Teeri; KTH; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; xyloglucan endo-transglycosylase; retaining glycoside hydrolase; glycosynthase; Pichia pastoris; fed-batch fermentation; expanded-bed adsorption; Plant biotechnology; Växtbioteknik;

    Abstract : The aim of this work was to develop a production process for the enzyme xyloglucan endo-transglycosylase from Populus tremula x tremuloides (PttXET16-34). The natural transglycosylating activity of this enzyme has previously been employed in a XET-Technology. READ MORE

  5. 3. Molecular modelling - understanding and prediction of enzyme selectivity

    Author : Linda Fransson; Karl Hult; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molecular modelling; regioselectivity; enantioselectivity; molecular dynamics; serine hydrolase; stereospecificity; Biochemistry; Biokemi;

    Abstract : Molecular modelling strategies for evaluation of enzyme selectivity wereinvestigated with a focus on principles of how molecular interactionscould be evaluated to provide information about selectivity. Althoughmolecular modelling provides tools for evaluation of geometrical andenergy features of molecular systems, no general strategies for evaluationof enzyme selectivity exist. READ MORE

  6. 4. Molecular modeling on reactions with lipases and related catalysts

    Author : Fredrik Haeffner; KTH; []
    Keywords : ;

    Abstract : The first part of this thesis discusses theories and methodsin the field of molecular modeling. A brief introduction to thequantum chemistry methods and the forte field methods is given. READ MORE

  7. 5. Studies on blood esterases : purification and characterization of a butyrylesterase from human erythrocytes

    Author : Benny Axenfors; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The object of these studies has been blood esterasesi and especially a butyrylesterase present in human erythrocytes. First, thiophenyl esters were synthesized for use as substrates in assaying arylesterases according to the ElIman procedure. READ MORE