Search for dissertations about: "serine metabolism"
Showing result 1 - 5 of 38 swedish dissertations containing the words serine metabolism.
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1. Examining the role of metabolism in Myc-driven tumorigenesis
Abstract : Myc transcriptionally regulates genes involved in processes such as cell proliferation, metabolism, differentiation, and angiogenesis. MYC expression is deregulated in many types of human cancer; therefore discovering the mechanisms behind MYCs role in tumorigenesis is essential. READ MORE
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2. Nitrogen and Redox Metabolism in Saccharomyces cerevisiae
Abstract : Anaerobic conversion of glucose to ethanol by the yeast Saccharomyces cerevisiae has been studied. Glycerol is formed as a by-product in order to maintain the overall redox balance. READ MORE
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3. Development and application of strategies for the analysis of modification patterns in chondroitin and dermatan sulphate
Abstract : Chondroitin (CS) and dermatan sulphate (DS) are socalled glycosaminoglycans (GAG) that are covalently attached to various type of proteins forming a subgroup within the diverse proteoglycan (PG) family. The PGs studied in this thesis are mostly extracellularly located and include aggrecan, biglycan and decorin. READ MORE
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4. Cyclic Nucleotide Phosphodiesterase 3B: Regulation in rat adipocytes and 3T3-L1 cells
Abstract : Insulin stimulation of rat adipocytes results in phosphorylation and activation of the cyclic nucleotide phosphodiesterase 3B (PDE3B), a key enzyme in the antilipolytic signalling pathway of this hormone. In this thesis, the site phosphorylated in PDE3B upon stimulation of rat adipocytes with insulin and/or the beta-adrenergic agonist, isoproterenol is identified. READ MORE
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5. Functional mapping and in vivo metabolism of the monoclonal antibody TS1 and its single-chain fragment : Its interaction with the antigen and the anti-idiotype
Abstract : Antibodies are proteins capable of specific interactions to a wide range of molecules. These interactions are facilitated by the complementary determining regions (CDR).Carcinomas are the most common of human cancers and they release significant amount of cytokeratins (CK) in the necrotic areas of the tumors. READ MORE