Search for dissertations about: "serotonin transporter polymorphism"

Showing result 1 - 5 of 7 swedish dissertations containing the words serotonin transporter polymorphism.

2. 1. Importance of serotonin-related candidate genes for human behaviour

   Author : Jonas Melke; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serotonin; genetics; polymorphism; association study; personality; panic disorder; premenstrual dysphoria; serotonin receptor; serotonin transporter;

   Abstract : Family and twin studies have been consistent in demonstrating that genetic factors are involved in the etiology of most major psychiatric disorders, as well as in various normal personality traits. Mostly due to the efficacy of serotonin-acting drugs, such as selective serotonin reuptake inhibitors (SSRI) and tricyclic antidepressants (TCA), the neurotransmitter serotonin has been implicated in a variety of common psychiatric disorders, including depression, a spectrum of anxiety disorders, and premenstrual dysphoria; moreover, some studies have suggested that also personality is influenced by serotonin. READ MORE

4. 2. Influence of serotonin-related genes on behavior and body weight

   Author : Jessica Bah Rösman; Göteborgs universitet; []
   Keywords : Serotonin; Genes; anorexia nervosa; premenstrual dysforia; body weight; suicide; polymorphism; HTR2C; SLC6A4; GATA2; HTR3B;

   Abstract : Rationale: The neurotransmitter serotonin has been implicated in the regulation of normal behaviors, including food intake, and attributed importance for a variety of common psychiatric conditions, including major depression, suicidal behavior, eating disorders and premenstrual dysphoria. The purpose of these studies was to explore the possible influence of genetic variation in serotonin-related genes on a) body weight, b) binding capacity of the serotonin transporter in the brain of suicide attempters and c) a disorder for which numerous findings suggest serotonin to play a key role, i. READ MORE

5. 3. On the influence of serotonin- and sex steroid-related genetic variation on mood, anxiety, personality, autism and transsexualism

   Author : Susanne Henningsson; Göteborgs universitet; []
   Keywords : serotonin; 5-HTTLPR; TPH2; 5-HT3; sex steroids; androgen receptor; estrogen receptor; genetics; gene-gene interaction; social phobia; anxiety; premenstrual dysphoric disorder; depression; personality; autism; transsexualism; amygdala; emotional perception; life events;

   Abstract : Background: The neurotransmitter serotonin has been related to mood and anxiety, and variation in genes that encode important members of the serotonergic system may hence affect mood- and anxiety-related traits. Sex steroids influence brain development, and variation in genes encoding androgen and estrogen receptors, or enzymes needed for sex steroid synthesis, may be of importance for both personality traits and risk for psychiatric disorders. READ MORE

6. 4. Molecular imaging of the serotonin system in human behaviour

   Author : Jacqueline Borg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : positron emission tomography; serotonin; 5-HT1A receptor; 5-HTT; 5HTTÖPR; WAY100635; MADAM; cognitive functions; personality;

   Abstract : The serotonin (5-HT) neurotransmission system has a role in essential physiological and psychological functions such as sleep, eating behaviour, sexuality, perception, emotion and cognition. Individual measures of serotonin biomarkers in the living human brain can be obtained using positron emission tomography (PET) imaging, direct measures of. READ MORE

7. 5. Suicide attempt and genes : psychiatric and genetic characteristics of suicide attempters

   Author : Maj-Liz Persson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Suicide; Attempted; Mental disorders; Association; Genetic markers; Serotonin; Norepinephrine; Dopamine;

   Abstract : Suicide affects an appreciable number of people in all societies. Finding genes that predispose to suicidal behavior may help to identify individuals at risk and an appropriate counseling and support can be extended to them. The studies of the present thesis focus on suicide attempt. READ MORE