Search for dissertations about: "serotonin"

Showing result 16 - 20 of 324 swedish dissertations containing the word serotonin.

  1. 16. From achiral to chiral analysis of citalopram

    Author : Björn Carlsson; Yngve Bergqvist; Linköpings universitet; []
    Keywords : depression; noradrenaline; dopamine; serotonin; citalopram; selective serotonin-reuptake inhibitor SSRI ; high-performance liquid chromatography HPLC ; therapeutic drug monitoring TDM ; enantioselective separation; MEDICINE; MEDICIN;

    Abstract : Within the field of depression the “monoamine hypothesis” has been the leading theory to explain the biological basis of depression. This theory proposes that the biological basis of depression is due to a deficiency in one or more of three key neurotransmitter systems, namely noradrenaline, dopamine and serotonin which are thought to mediate the therapeutic actions of virtually every known antidepressant agent. READ MORE

  2. 17. Imaging Anxiety : Neurochemistry in Anxiety Disorders Assessed by Positron Emission Tomography

    Author : Andreas Frick; Mats Fredrikson; Tomas Furmark; David J Nutt; Uppsala universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Fear; Brain; Serotonin; Neurokinin; Substance P; Psychology; Psykologi;

    Abstract : Anxiety disorders, including social anxiety disorder (SAD) and posttraumatic stress disorder (PTSD) are common and disabling conditions. Largely based on animal and pharmacological studies, both the serotonergic and substance P/neurokinin-1 (SP/NK1) systems have been implicated in their underlying pathology. READ MORE

  3. 18. Reactive oxygen species as signalling molecules in immunity

    Author : Åsa Betten; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reactive oxygen species; NK cells; phagocytes; serotonin; histamine; myeloperoxidase;

    Abstract : Cytotoxic lymphocytes such as natural killer (NK) cells and subsets of T cells are key components of the host defense against malignancy and infection. Earlier studies have demonstrated that NK cells and several phenotypes of T cells become dysfunctional and apoptotic after exposure to autologous monocyte/macrophages and other phagocytes. READ MORE

  4. 19. On the association between panic disorder and autonomic regulation – With special focus on the roles of respiration and on the catechol-O-methyltransferase gene

    Author : Kristina Annerbrink; Göteborgs universitet; []
    Keywords : panic disorder; serotonin; respiration; polymorphism; COMT Val158Met; HCRTR2 G1246A; blood pressure; anthropometry;

    Abstract : Background and aims: Panic disorder is a psychiatric disorder characterized by sudden attacks of intense anxiety. It displays a lot of features suggesting that it may be associated with an underlying aberration in the autonomic regulation of heart activity and respiration: i) the attacks are often characterized by respiratory symptoms and symptoms from the heart, ii) the attacks can be elicited by respiratory stimulants, iii) between attacks, patients with panic disorder often display enhanced respiratory variability and reduced heart rate variability, and iv) patients with panic disorder display enhanced prevalence of respiratory disorders and enhanced mortality in cardiovascular disease. READ MORE

  5. 20. Monoaminergic modulation in spinal reflex pathways from group I afferents

    Author : Ingela Hammar; Göteborgs universitet; []
    Keywords : primary afferents; spinal interneurones; ventral spinocerebellar tract neurones; noradrenaline; serotonin; cat;

    Abstract : Serotonin and noradrenaline are known to play an important part in modulation of spinal neuronal networks. Group I muscle afferents mediate information on dynamic changes of muscle length and tension, and modulation of actions from these afferents could be of importance for the execution of movements. READ MORE