Search for dissertations about: "serpin"
Showing result 1 - 5 of 10 swedish dissertations containing the word serpin.
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1. Human Glandular Kallikrein 2
Abstract : Human glandular kallikrein 2 (hK2) is a serine protease, which is predominantly expressed by the prostate gland and found in seminal plasma at mean levels of 6 mg/ml. It has 79% amino acid sequence identity with prostate-specific antigen (PSA or hK3). READ MORE
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2. Plasminogen activator inhibitor type 2 : a unique serpin with two mobile loops
Abstract : The superfamily of serine protease inhibitors (serpins) is a large group of proteins with diverse functions but a common tertiary structure. Active serpins are highly metastable molecules. Metastability is the property underlying the success and ubiquitousness of serpins. READ MORE
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3. Plasminogen activator inhibitor type-1 : structure-function studies and its use as a reference for intramolecular distance measurements
Abstract : Inhibitors belonging to the serpin (serine protease inhibitor) family control proteases involved in various physiological processes. All serpins have a common tertiary structure based on the dominant b-sheet A, but they have different inhibitory specificity. READ MORE
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4. Hydrophobic interactions of serpins
Abstract : The proteins of the serpin family are primarily but not exclusively proteinase inhibitors, which share a common, similar structure. It is known that this structure undergoes major conformational changes upon cleavage in the serpin reactive site loop, and that these changes include rearrangements within the hydrophobic core of the molecule. READ MORE
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5. A New Look into Protein C Inhibitor : Posttranslational Modifications and their Functions
Abstract : The influences of posttranslational modifications on the functions of the versatile serpin protein C inhibitor (PCI) were studied. PCI is a serine protease inhibitor that is expressed in many tissues and secreted to various fluids in human, including blood plasma, seminal plasma, and urine. READ MORE