Search for dissertations about: "sertraline"

Showing result 11 - 15 of 20 swedish dissertations containing the word sertraline.

  2. 11. Transition metal- and lipase-catalyzed reactions : Dynamic resolutions, hydrogen transfer and enzyme engineering

    Author : Patrik Krumlinde; Jan-Erling Bäckvall; Johannes G. de Vries; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Dynamic kinetic resolution; dynamic kinetic asymmetric transformation; hydrogen transfer; directed evolution; enzyme engineering; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : This thesis mainly focuses on chemoenzymatic processes and can be divided into three parts: The first part of the thesis, chapters 2-4, is devoted to the development of combined ruthenium- and enzyme-catalyzed dynamic processes. In these processes the metal catalyst racemizes (epimerizes) the alcohol substrate via hydrogen transfer and the enzyme transforms the substrate into enantiomerically enriched product. READ MORE

  4. 12. Adherence to Antidepressant Medication

    Author : Ann-Charlotte Åkerblad; Lisa Ekselius; Ingvar Krakau; Uppsala universitet; []
    Keywords : Psychiatry; adherence; depression; randomised controlled trial; intervention; therapeutic drug monitoring; personality; health status; health care utilisation; Psykiatri;

    Abstract : Non-adherence to medication is a major obstacle in the treatment of depression. The objectives of the present study were to explore the effect of two interventions aiming to increase antidepressant treatment adherence, and to examine long-term consequences and costs of depression in adherent and non-adherent primary care patients. READ MORE

  5. 13. Serotonin system in Alzheimer’s disease : from a molecular and biomarkers perspective

    Author : Walid Tajeddinn Abderhim; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Serotonin, 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter with a wide range of biological functions. It contributes to the integrity, connectivity and function of the central nervous system (CNS). READ MORE

  6. 14. New Molecular Approaches to Glioblastoma Therapy

    Author : Sathishkumar Baskaran; Sven Nelander; Karin Forsberg Nilsson; Silvia Marino; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; GBM; ZBTB16; PLZF; Heterogeneity; Proteasome inhibitors; Bortezomib; Pterostilbene; drug combinations; Oncology; Onkologi; Biological Research on Drug Dependence; Biologisk beroendeforskning; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap; Medicinsk vetenskap; Medical Science; Molekylär medicin; Molecular Medicine;

    Abstract : Glioblastoma (GBM) is the most common high-grade brain tumor diagnosed in patients who are more than 50 years of age. The standard of care treatment is surgery, followed by radiotherapy and chemotherapy. The median life expectancy of patients is only between 12 to 15 months after receiving current treatment regimes. READ MORE

  7. 15. Drug use during pregnancy with focus on antidepressants

    Author : Emelie Wolgast; Ann Josefsson; Caroline Lilliecreutz; Margareta Reis; Karin Sjöström; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Background: More than half of pregnant women use at least one prescribed medication during pregnancy, and almost all pregnant women use some kind of over-the-counter medication. Depression is one of the most common diseases in the world today, also during the peripartum period. READ MORE